Observational studyBMC infectious diseases2024
Evaluation of clinical outcomes and risk factors associated with mortality in patients with Stenotrophomonas maltophilia bloodstream infection: a multicenter study.
Observational study in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Female Sex and Mortality in Patients With Gram-Negative Bacteremia: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Treatment Patterns and Clinical Outcomes in Children withMicroorganisms · 2026Article
- Molecular Regulation of Biofilm Development inPathogens (Basel, Switzerland) · 2026Review
- Clinical, microbiological, and molecular characteristics, outcomes, and risk factors for mortality of patients with Stenotrophomonas maltophilia bloodstream infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Navigating the Challenges ofClinical case reports · 2026Article
- Independent Predictors of 28-Day Mortality and the Critical Role of Source Control inPathogens (Basel, Switzerland) · 2026Article
- Risk factors for mortality in Stenotrophomonas maltophilia bacteraemia: a 22-year retrospective study in a Japanese acute care hospital.Access microbiology · 2026Article
- Review
- Clinical characteristics and factors associated with in-hospital mortality in patients withFrontiers in medicine · 2026Article
- The Other Face ofAntibiotics (Basel, Switzerland) · 2026Article
- What Drives Mortality inMicroorganisms · 2025Article
- Epidemiological and Clinical Characteristics ofTropical medicine and infectious disease · 2025Article
- Propensity-Matched Comparison of Timely vs Delayed Antibiotic Therapy inOpen forum infectious diseases · 2025Article
- Correction: Evaluation of clinical outcomes and risk factors associated with mortality in patients with Stenotrophomonas maltophilia bloodstream infection: a multicenter study.BMC infectious diseases · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStenotrophomonas maltophilia, a pathogen that colonizes medical equipment and causes nosocomial infections due to its ability to form biofilms, has high mortality rates. This study investigated the risk factors related to mortality in patients who were diagnosed with S. maltophilia bacteremia.
methodsIt is a multi-center, retrospective ad observational cohort study. The demographic characteristics, clinical findings, microbiological data, and risk factors for patients were obtained from the medical records of patients at ten different hospitals between January 1, 2018, and June 30, 2023.
resultsThe study included a total of 321 patients. The observed thirty-day mortality rate was 46.1%. A central venous catheter (CVC) was present in 276 patients (86%), and in 66 of these patients (23.9%) the CVC was removed. While only 18 patients (5.6%) received appropriate empirical antibiotics, 242 (75.4%) patients received appropriate antibiotics according to antimicrobial susceptibility test (AST) results and treatment revisions. Multivariate analysis revealed that advanced age (hazard ratio [HR] = 1.02; 95% confidence interval [CI]: 1.00- 1.03), appropriate antibiotic treatment (HR = 0.35; 95% CI: 0.23-0.52), and removal of central venous catheters (HR = 0.31; 95% CI: 0.16-0.60) were significantly related to reduced mortality.
conclusionsS. maltophilia is a significant pathogen, and to reduce its high mortality rate, removal of the CVC and switching to appropriate antibiotics should be performed as soon as possible.
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