ArticleNPJ digital medicine2024
The real-world association between digital markers of circadian disruption and mental health risks.
Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed.
- Feasibility of longitudinal sleep monitoring among Kenyan healthcare workers using wearable technology.Research square · 2026Article
- Essential Information About Chronobiology and Chronotherapy for the Optimal Care of People With Bipolar Disorders: An Expert Consensus.Bipolar disorders · 2026Article
- Time vortex: the circadian-dopaminergic dialogue in Parkinson's disease.NPJ Parkinson's disease · 2026Review
- Smartphone-based digital phenotyping for detection of high-risk depression and anxiety in Korean community settings.Internet interventions · 2026Article
- Circadian Phase Estimation From Ambulatory Wearables With Particle Filtering: Accuracy Depends on Initialization, Recording Duration, and Light Exposure.Journal of biological rhythms · 2026Article
- Article
- Sleep duration moderates association between screen time and emotional and behavioural problems in young children.World journal of pediatrics : WJP · 2025Article
- Long term monitoring shows phase lagged behaviorally driven locomotor autonomic coupling.Scientific reports · 2025Article
- Circadian Biomarkers in Humans: Methodological Insights into the Detection of Melatonin and Cortisol.Biomolecules · 2025Review
- Seasonal timing and interindividual differences in shiftwork adaptation.NPJ digital medicine · 2025Article
- Forecasting the course of bipolar disorder using rest-activity rhythms: Protocol for a multi-study modelling project.Wellcome open research · 2025Article
- Associations of sunlight affinity with depression and sleep disorders in American males: Evidence from NHANES 2009-2020.PloS one · 2025Article
- Rest-activity rhythmicity as digital biomarkers of postoperative recovery and complications in children.Digital healthArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While circadian disruption is recognized as a potential driver of depression, its real-world impact is poorly understood. A critical step to addressing this is the noninvasive collection of physiological time-series data outside laboratory settings in large populations. Digital tools offer promise in this endeavor. Here, using wearable data, we first quantify the degrees of circadian disruption, both between different internal rhythms and between each internal rhythm and the sleep-wake cycle. Our analysis, based on over 50,000 days of data from over 800 first-year training physicians, reveals bidirectional links between digital markers of circadian disruption and mood both before and after they began shift work, while accounting for confounders such as demographic and geographic variables. We further validate this by finding clinically relevant changes in the 9-item Patient Health Questionnaire score. Our findings validate a scalable digital measure of circadian disruption that could serve as a marker for psychiatric intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.