Evidence map›Paper›PMID 39639064›Full record

ArticleScientific reports2024

Toll-like receptor 3 signaling attenuated colitis-associated cancer development in mice.

Kee Young Chung, Seulji Kim, Hee Tae Yoon, So Hyun Kwon, Hyun Sun Park, Jong Pil Im, Joo Sung Kim, Ji Won Kim, Yoo Min Han, Seong-Joon Koh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kee Young ChungDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.
Seulji KimDivision of Gastroenterology, Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
Hee Tae YoonLaboratory of Intestinal Mucosa and Skin Immunology, Seoul National University College of Medicine, Seoul, Korea.
So Hyun KwonLaboratory of Intestinal Mucosa and Skin Immunology, Seoul National University College of Medicine, Seoul, Korea.
Hyun Sun ParkLaboratory of Intestinal Mucosa and Skin Immunology, Seoul National University College of Medicine, Seoul, Korea.
Jong Pil ImDivision of Gastroenterology, Department of Internal medicine, Seoul National University Hospital, Seoul, Korea.
Joo Sung KimDivision of Gastroenterology, Department of Internal medicine, Seoul National University Hospital, Seoul, Korea.
Ji Won KimDivision of Gastroenterology, Department of Internal medicine, SMG-SNU Boramae Medical Center, Seoul, Korea.
Yoo Min HanLaboratory of Intestinal Mucosa and Skin Immunology, Seoul National University College of Medicine, Seoul, Korea.
Seong-Joon KohDepartment of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. jel1206@snu.ac.kr.ORCID 0000-0001-8001-8777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease is associated with a high risk of colitis-associated cancer (CAC). We evaluated the role of TLR3 in CAC using a murine model. Wild-type (WT) and TLR3-knockout (TLR3

Indexed as

AzoxymethaneColitisColitis-Associated NeoplasmsMice, KnockoutSignal TransductionToll-Like Receptor 3Animalsbeta CateninColonDextran SulfateDisease Models, AnimalMaleMiceMice, Inbred C57BLPoly I-CAzoxymethanebeta CateninDextran SulfatePoly I-CTLR3 protein, mouseToll-Like Receptor 3

Identifiers

PMID39639064
PMCPMC11621332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.