Evidence map›Paper›PMID 39639027›Full record

ArticleNature communications2024

Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32.

Samara Mishelle Ona Chuquimarca, Jonah Beenstock, Salima Daou, Jennifer Porat, Alexander F A Keszei, Jay Z Yin, Tobias Beschauner, Mark A Bayfield, Mohammad T Mazhab-Jafari, Frank Sicheri

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Catalytic and regulatory basis of tRNA tNature communications · 2026
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Samara Mishelle Ona Chuquimarca *Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.
Jonah Beenstock *Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, M5G 1X5, Canada. beenstock@lunenfeld.ca.
Salima DaouLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, M5G 1X5, Canada.
Jennifer PoratDepartment of Biology, York University, Toronto, ON, M3J 1P3, Canada.ORCID http://orcid.org/0000-0002-1709-4635
Alexander F A KeszeiPrincess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, M5G 2C4, Canada.
Jay Z YinLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, M5G 1X5, Canada.
Tobias BeschaunerLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, M5G 1X5, Canada.
Mark A BayfieldDepartment of Biology, York University, Toronto, ON, M3J 1P3, Canada.ORCID http://orcid.org/0000-0002-8971-7598
Mohammad T Mazhab-JafariPrincess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, M5G 2C4, Canada.
Frank SicheriDepartment of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada. sicheri@lunenfeld.ca.ORCID http://orcid.org/0000-0002-9824-2117

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) PJT-178026
6 · The paper itself

Abstract

The enzyme complex KEOPS (Kinase, Endopeptidase and Other Proteins of Small size) installs the universally conserved and essential N

Indexed as

Cryoelectron MicroscopyRNA, TransferAdenosineAdenosine TriphosphatasesHumansModels, MolecularMultienzyme ComplexesProtein BindingProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdenosineAdenosine TriphosphatasesBUD32 protein, S cerevisiaeKEOPS complex, S cerevisiaeMultienzyme ComplexesN(6)-(N-threonylcarbonyl)adenosineProtein Serine-Threonine KinasesRNA, TransferSaccharomyces cerevisiae Proteins

Identifiers

PMID39639027
PMCPMC11621456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.