Evidence map›Paper›PMID 39639018›Full record

ReviewNature reviews. Disease primers2024

Body dysmorphic disorder.

Christian Rück, David Mataix-Cols, Jamie D Feusner, Roseli Gedanke Shavitt, David Veale, Georgina Krebs, Lorena Fernández de la Cruz

Registry-linked trialAbstract readReview
In one paragraph

Review in Nature reviews. Disease primers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07521813 (Evaluation of Body Dysmorphic Disorder in Children With Dermatological Diseases), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07521813 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of Body Dysmorphic Disorder in Children With Dermatological Diseases

TypeobservationalSponsorSohag UniversityRan2026 to 2027Enrolled500ConditionsBody Dysmorhpic DisorderArmsQuestionnaire and Physical Exam
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  13. Eating disorders and the incel community.Frontiers in psychology · 2026
    Article
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  15. Review
  16. Body Dysmorphic Disorder and Risperidone Abuse: Exploiting Hyperprolactinemia.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christian RückCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Healthcare Services, Region Stockholm, Stockholm, Sweden. christian.ruck@ki.se.ORCID http://orcid.org/0000-0002-8742-0168
David Mataix-ColsCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Healthcare Services, Region Stockholm, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-4545-0924
Jamie D FeusnerCentre for Addiction and Mental Health, Toronto, Ontario, Canada.
Roseli Gedanke ShavittObsessive-Compulsive Spectrum Disorders Program, LIM23, Hospital das Clinicas HCFMUSP, Instituto & Departamento de Psiquiatria da Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
David VealeSouth London and Maudsley NHS Foundation Trust, London, UK.
Georgina KrebsResearch Department of Clinical, Educational, and Health Psychology, University College London, London, UK.
Lorena Fernández de la CruzCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Healthcare Services, Region Stockholm, Stockholm, Sweden.

Funding

Neural mechanisms of perceptual abnormalities and their malleability in bodydysmorphic disorderR01MH121520 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FEUSNER, JAMIE · 2020 to 2025
$2.8M
Exogenous Modulation of Visual Perception And Connectivity in Body Dysmorphic Disorder (EMPAC-BDD)R21MH128815 · NIMH · CENTRE FOR ADDICTION AND MENTAL HEALTH · PI FEUSNER, JAMIE · 2022 to 2023
$273k
NIMH NIH HHS R01 MH121520NIMH NIH HHS R21 MH128815
6 · The paper itself

Abstract

Body dysmorphic disorder (BDD) is an obsessive-compulsive disorder-related psychiatric condition characterized by an intense preoccupation with perceived physical flaws that are not observable by others. BDD affects ~2% of the adult population but is underdiagnosed, partly owing to limited clinician awareness, and undertreated, partly due to limited access to treatment. Research on the aetiology of BDD is scarce but likely involves an interplay between genetic and environmental factors. A few studies suggest functional and structural brain differences (compared with controls) in the regions involved in visual and emotional processing, although firm conclusions about the pathophysiology of the disorder cannot be made at this stage. Diagnosis requires the presence of repetitive behaviours or mental acts typically aimed at checking, correcting or concealing perceived flaws. The disorder typically has its onset before 18 years of age, with a female preponderance in youth but no major gender disparity in adults. Quality of life is markedly impaired across multiple domains and suicide risk is considerable. Evidence-based treatments include cognitive behavioural therapy and selective serotonin reuptake inhibitors. Future research should focus on understanding the biological and environmental factors that increase the risk of BDD, and on improving access to effective treatments, thereby addressing a critical gap in care for this often misunderstood and overlooked disorder.

Indexed as

Body Dysmorphic DisordersAdultCognitive Behavioral TherapyFemaleHumansMaleObsessive-Compulsive DisorderQuality of LifeSelective Serotonin Reuptake InhibitorsSelective Serotonin Reuptake Inhibitors

Identifiers

PMID39639018
PMCPMC12032537

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.