Evidence map›Paper›PMID 39638889›Full record

ReviewAAPS PharmSciTech2024

Cyclodextrin Drugs in Liposomes: Preparation and Application of Anticancer Drug Carriers.

Lanni Feng, Ruting Wei, Jiali Wu, Xinmei Chen, Yan Wen, Jianming Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lanni Feng *Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Ruting Wei *Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Jiali Wu *Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China.
Xinmei ChenShanghai WeiEr Lab, Shanghai, 201707, China.
Yan WenDepartment of Pharmacy, Changzheng Hospital, Naval Medical University, No.415, Fengyang Road, Shanghai, 200003, China.
Jianming ChenDepartment of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122, China. chenjm0711@163.com.ORCID http://orcid.org/0000-0001-8773-8494

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclodextrin complexes have been widely used in pharmaceutical applications, but disadvantages such as the rapid clearance of cyclodextrins from the blood stream after in vivo administration or their replacement by other molecules in the biological medium with higher luminal affinity for cyclodextrins limit the application of cyclodextrins as drug carriers. Liposome-encapsulated hydrophobic drugs have low and unstable drug loading rates. Drug-in-CD-in-liposome (DCL), which encapsulate cyclodextrin inclusion complexes into liposomes, combine the advantages of both delivery systems, can effectively avoid the leakage and rapid release of lipophilic drugs in the lipid bilayer, and help to maintain the integrity of liposomes. This paper focuses on the preparation method, characterization and application of DCL, with a view to providing methods and references for the research and application of DCL technology.

Indexed as

Antineoplastic AgentsCyclodextrinsDrug CarriersLiposomesChemistry, PharmaceuticalDrug CompoundingDrug Delivery SystemsHumansHydrophobic and Hydrophilic InteractionsAntineoplastic AgentsCyclodextrinsDrug CarriersLiposomesanti-cancer drugsapplicationcyclodextrinliposomespreparation method

Identifiers

PMID39638889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.