Evidence map›Paper›PMID 39638302›Full record

Observational studyJournal of preventive medicine and public health = Yebang Uihakhoe chi2025

Development and Validation of an Instrument to Assess the Safe Use of Antidiabetic Medication to Prevent Hypoglycemia Requiring Hospitalization Among Ambulatory Patients With Type 2 Diabetes Mellitus in Bali, Indonesia.

Made Krisna Adi Jaya, Fita Rahmawati, Nanang Munif Yasin, Zullies Ikawati

Abstract readValidation StudyObservational Study
In one paragraph

Observational study in Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Made Krisna Adi JayaFaculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Fita RahmawatiFaculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Nanang Munif YasinFaculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Zullies IkawatiFaculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Funding

Center for Higher Education FundingEndowment Funds for EducationIndonesia Center for Education Financial Services 00438/BPPT/BPI.06/9/2023
6 · The paper itself

Abstract

objectivesAmbulatory patients with type 2 diabetes mellitus (T2DM) require special attention when being discharged from the hospital with anti-diabetes medication. This necessity stems primarily from the risk of adverse drug reactions, particularly hypoglycemia. However, this risk is significantly influenced by the patients' knowledge and behavior regarding their medication use. This study aimed to develop instrument to assess the risk of medication-related hypoglycemia in ambulatory T2DM patients by clinical pharmacists.

methodsThe study was conducted using an observational design that included multiple stages. These stages involved item development through focus group discussions (FGDs), content validation by clinical pharmacists, and criterion and construct validation by ambulatory T2DM patients using a cross-sectional approach.

resultsA total of 10 question items were developed for assessment by clinical pharmacists following FGDs and content validation. Criterion and construct validation identified 8 valid question items through multivariate analysis (p<0.05). The scoring system developed demonstrated a linear relationship between the score and the number of items at risk in the instrument (p<0.05, R²=0.988). Additionally, the instrument was named "Medication-related Hypoglycemia Risk Score Assessment Tools (HYPOGLYRISK)."

conclusionsThe findings of this study suggest that HYPOGLYRISK may serve as a useful tool for clinical pharmacists to evaluate the risk of medication-related hypoglycemia in ambulatory T2DM patients. Additionally, this instrument could assist clinical pharmacists in identifying priority patients and tailoring educational services to meet their specific goals and needs.

Indexed as

Diabetes Mellitus, Type 2HypoglycemiaHypoglycemic AgentsAdultAgedCross-Sectional StudiesFemaleFocus GroupsHospitalizationHumansIndonesiaMaleMiddle AgedPharmacistsSurveys and QuestionnairesHypoglycemic AgentsAmbulatory type 2 diabetes mellitusClinical pharmacyHypoglycemiaMedication safety

Identifiers

PMID39638302
PMCPMC11824621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.