Evidence map›Paper›PMID 39637928›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2025

The Impact and Interactions of Race and Gender on Healthcare Use and Spending in Irritable Bowel Syndrome.

Andrea Shin, Rachel Sarnoff, Arpana Church, Huiping Xu, Lin Chang

Abstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cost-of-Illness of Irritable Bowel Syndrome: A Systematic Review.Journal of gastroenterology and hepatology · 2026
    Pooled it
  2. Article
  3. Health Disparities in Irritable Bowel Syndrome.Gastroenterology & hepatology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrea ShinVatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, California. Electronic address: asshin@mednet.ucla.edu.
Rachel SarnoffVatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, California.
Arpana ChurchVatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, California.
Huiping XuDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana.
Lin ChangVatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, California.

Funding

The role of brain-gut microbiome interactions in mediating IBS and constipation symptoms during menses and menopauseU54DK123755 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Lin Chang, Elaine Hsiao · 2020 to 2026
$10.5M
NIDDK NIH HHS U54 DK123755
6 · The paper itself

Abstract

BACKGROUND &

aimsStudies examining the effects of social determinants of health on healthcare use in irritable bowel syndrome (IBS) are scarce. We aimed to assess healthcare spending among different racial/ethnic groups and genders in adults with IBS.

methodsWe performed a retrospective cohort analysis of adults diagnosed with IBS between 2016 and 2021 using Optum's de-identified Clinformatics Data Mart database. We analyzed total annual and IBS-specific costs, utilization and costs of individual services, and prescriptions. We compared outcomes across racial/ethnic groups and by gender after adjusting for covariates and examined race-gender interactions.

resultsAmong 95,319 adults with IBS, healthcare spending varied significantly by race and gender. Total all-cause and IBS-specific costs were lower in men than in women and in Asian and Hispanic patients than in White patients. Compared with White patients, Black patients had higher total IBS-specific costs, all-cause prescription costs, IBS-related radiology and laboratory costs, and emergency department (ED) care, while Asian and Hispanic patients incurred lower costs for ED care, hospitalizations, and all-cause prescriptions. Endoscopy costs were lower in racial minority groups. Women had higher spending for most services compared with men, but gender differences in most IBS-related services were small. All-cause hospitalization and endoscopy costs were higher in men, but IBS-specific hospitalization and endoscopy costs were higher in women. Gender disparities in all-cause individual services also varied by race.

conclusionsOverall and IBS-related spending is higher in women, but gender differences in IBS-related care are small. Racial/ethnic comparisons show reduced spending in Asian and Hispanic patients, increased ED care in Black patients, and variations in spending patterns. Gender disparities differ by race.

Indexed as

EthnicityHealth Care CostsIrritable Bowel SyndromePatient Acceptance of Health CareRacial GroupsAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSex FactorsUnited StatesYoung AdultDisorders of Gut-Brain InteractionEconomic BurdenFunctional Gastrointestinal DisordersIrritable Bowel SyndromeSex

Identifiers

PMID39637928
PMCPMC13147302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.