ArticleNeurobiology of aging2025
Relationships of functional connectivity of motor cortex, primary somatosensory cortex, and cerebellum to balance performance in middle-aged and older adults.
Article in Neurobiology of aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Effects of Different Repetitive Transcranial Magnetic Stimulation Targets for Enhancing Motor Learning: A Single-Blind Randomized Controlled Trial.Neural plasticity · 2026Trial
- Enhancing Balance Control in Aging Through Cerebellar Theta-Burst Stimulation.Cerebellum (London, England) · 2025Trial
- Altered microbial cargo in fecal microbiome-derived outer membrane vesicles as novel biomarkers for vascular dementia.BMC microbiology · 2026Article
- Functional and structural connectome-based predictive modelling of balance in elderly adults.Scientific reports · 2026Article
- Sub-Regional Motor-Somatosensory Connectivity and Lifespan Plasticity in Functional Networks.Neurosciences (Riyadh, Saudi Arabia) · 2026Article
- Cerebellar Purkinje cell firing reduction contributes to aging-related declining motor coordination in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Altered activation patterns of sensorimotor cortex during level walking and stair climbing in patients with knee osteoarthritis: a cross-sectional study.Frontiers in aging neuroscience · 2026Article
- Cerebellar transcranial direct current stimulation combined with virtual reality training for the balance of older adults: study protocol for a randomized controlled trial.BMC complementary medicine and therapies · 2025Article
- Reduced parietal to frontal functional connectivity for dynamic balance in late middle-to-older adults.Experimental brain research · 2025Article
- Differences in sensory-motor cortex activation patterns during level and stair walking in patients with knee osteoarthritis: protocol for a cross-sectional study.Frontiers in aging neuroscience · 2025Article
- Joint-level proprioceptive deficits and postural instability in Fibromyalgia: a biomechanical assessment using digital inclinometry and dynamic posturography.Frontiers in bioengineering and biotechnology · 2025Article
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Abstract
Connectivity of somatosensory cortex (S1) and cerebellum with the motor cortex (M1) is critical for balance control. While both S1-M1 and cerebellar-M1 connections are affected with aging, the implications of altered connectivity for balance control are not known. We investigated the relationship between S1-M1 and cerebellar-M1 connectivity and standing balance in middle-aged and older adults. Our secondary objective was to investigate how cognition affected the relationship between connectivity and balance. Our results show that greater S1-M1 and cerebellar-M1 connectivity was related to greater postural sway during standing. This may be indicative of an increase in functional recruitment of additional brain networks to maintain upright balance despite differences in network connectivity. Also, cognition moderated the relationship between S1-M1 connectivity and balance, such that those with lower cognition had a stronger relationship between connectivity and balance performance. It may be that individuals with poor cognition need increased recruitment of brain regions (compensation for cognitive declines) and in turn, higher wiring costs, which would be associated with increased functional connectivity.
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