Evidence map›Paper›PMID 39637338›Full record

ArticleJCO precision oncology2024

Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Harboring

Alessandro Di Federico, Stefania Angelicola, Mariateresa Frascino, Irene Siracusa, Beatrice Bisanti, Francesca Ruzzi, Maria Sofia Semprini, Hugo De Jonge, Andrea De Giglio, Francesca Sperandi and 9 more

Erratum issuedAbstract readCase Reports
In one paragraph

Article in JCO precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Alessandro Di FedericoMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0001-8877-4315
Stefania AngelicolaMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0001-9495-5147
Mariateresa FrascinoDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Irene SiracusaDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Beatrice BisantiDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Francesca RuzziLaboratory of Immunology and Biology of Metastasis, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.ORCID 0000-0001-9555-3166
Maria Sofia SempriniLaboratory of Immunology and Biology of Metastasis, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.ORCID 0000-0001-5013-6908
Hugo De JongeDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.ORCID 0000-0003-2777-4084
Andrea De GiglioMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-0731-5721
Francesca SperandiMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-1581-3456
Stefano BrocchiDepartment of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-7563-8936
Barbara MelottiMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Francesca GiunchiPathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0001-5298-939X
Elisa GruppioniSolid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-4334-6170
Annalisa AltimariSolid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0001-9944-2455
Pier-Luigi LolliniLaboratory of Immunology and Biology of Metastasis, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.ORCID 0000-0003-1702-4108
Andrea ArdizzoniMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Arianna PalladiniDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.ORCID 0000-0001-6105-4895
Francesco GelsominoMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0002-9204-1728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with tumors harboring MATERIALS AND

methodsTwo patients with

resultsPatient 1, a 60-year-old male with BRAF

conclusion

Indexed as

Carcinoma, Non-Small-Cell LungErbB ReceptorsLung NeoplasmsMutationProtein Kinase InhibitorsProto-Oncogene Proteins B-rafCell Line, TumorErlotinib HydrochlorideFemaleHumansMaleMiddle AgedTyrosine Kinase InhibitorsBRAF protein, humanEGFR protein, humanErbB ReceptorsErlotinib HydrochlorideProtein Kinase InhibitorsProto-Oncogene Proteins B-rafTyrosine Kinase Inhibitors

Identifiers

PMID39637338
PMCPMC11661570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.