Evidence map›Paper›PMID 39637324›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

FGF21 Signaling Exerts Antifibrotic Properties during Pulmonary Fibrosis.

Mada Ghanem, Gabrielle Archer, Aurélien Justet, Madeleine Jaillet, Eirini Vasarmidi, Pierre Mordant, Yves Castier, Hervé Mal, Aurélie Cazes, Nicolas Poté and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Inter-Organ Communication in Pulmonary Fibrosis: Systemic Modifiers of a Lung-Centered Disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  4. [Fibroblast growth factor 21 improves alcoholic liver disease by regulating gut microbiota in mice].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Pulmonary fibrosis: from mechanisms to therapies.Journal of translational medicine · 2025
    Review
  12. From Liver Insights to Lung Innovations: FGF21 and Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2025
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Mada GhanemFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Gabrielle ArcherFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Aurélien JustetFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Madeleine JailletFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Eirini VasarmidiFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Pierre MordantService de Chirurgie Thoracique et Vasculaire.
Yves CastierService de Chirurgie Thoracique et Vasculaire.
Hervé MalService de Pneumologie et Transplantation.
Aurélie CazesFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Nicolas PotéFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Bruno CrestaniFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.
Arnaud MailleuxFaculté de Médecine Xavier Bichat, Université Paris Cité, Institut National de la Santé et de la Recherche Médicale, UMR1152, FHU APOLLO, Labex INFLAMEX, Paris, France; and.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Fibroblast Growth FactorsIdiopathic Pulmonary FibrosisSignal TransductionAgedAnimalsApoptosisBleomycinDisease Models, AnimalFemaleFibroblastsHumansMaleMiceMice, Inbred C57BLMiddle AgedBleomycinFGF21 protein, humanfibroblast growth factor 21Fibroblast Growth Factorsalveolar epithelial cellsbleomycinFGF21idiopathic pulmonary fibrosisKLB

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.