Evidence map›Paper›PMID 39637288›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2025

Links Between Early Prelinguistic Communication and Later Expressive Language in Toddlers With Autistic and Non-Autistic Siblings.

Jennifer E Markfeld, Zoë Kiemel, Pooja Santapuram, Samantha L Bordman, Grace Pulliam, S Madison Clark, Lauren H Hampton, Bahar Keçeli-Kaysili, Jacob I Feldman, Tiffany G Woynaroski

Abstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Relations Between Preferential Looking to Synchronous Audiovisual Speech and Expressive Language in Infants With Autistic and Non-Autistic Siblings.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jennifer E MarkfeldDepartment of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.ORCID 0000-0002-7995-6077
Zoë KiemelDepartment of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.ORCID 0009-0002-2252-8335
Pooja SantapuramVanderbilt University School of Medicine, Nashville, TN.
Samantha L BordmanDepartment of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.
Grace PulliamNeuroscience Graduate Program, Vanderbilt University, Nashville, TN.
S Madison ClarkNeuroscience Undergraduate Program, Vanderbilt University, Nashville, TN.
Lauren H HamptonDepartment of Special Education, The University of Texas at Austin.ORCID 0000-0002-4137-9307
Bahar Keçeli-KaysiliDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0003-2187-2775
Jacob I FeldmanFrist Center for Autism and Innovation, Vanderbilt University, Nashville, TN.ORCID 0000-0002-5723-5834
Tiffany G WoynaroskiFrist Center for Autism and Innovation, Vanderbilt University, Nashville, TN.ORCID 0000-0001-6513-1181

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R01DC020186 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tiffany Woynaroski · 2022 to 2026
$3.2M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)KL2TR000446 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$2.8M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R21DC016144 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WOYNAROSKI, TIFFANY · 2017 to 2019
$474k
Evaluating Cascading Effects of Caregiver Stress on Later Language Outcomes of InfantsF31DC022173 · NIDCD · VANDERBILT UNIVERSITY · PI MAGNUSON, JENNIFER E · 2024 to 2025
$52k
NCATS NIH HHS KL2 TR000446NICHD NIH HHS P50 HD103537NIDCD NIH HHS F31 DC022173NIDCD NIH HHS R01 DC020186NIDCD NIH HHS R21 DC016144
6 · The paper itself

Abstract

purposeThe present study explored the extent to which early prelinguistic communication skills predict expressive language in toddlers with autistic siblings (Sibs-autism), who are known to be at high likelihood for autism and language disorder, and a comparison group of toddlers with non-autistic older siblings (Sibs-NA).

methodParticipants were 51 toddlers (29 Sibs-autism, 22 Sibs-NA) aged 12-18 months at the first time point in the study (Time 1). Toddlers were seen again 9 months later (Time 2). Three prelinguistic communication skills (i.e., intentional communication, vocalization complexity, and responding to joint attention) were measured at Time 1 via the Communication and Symbolic Behavior Scales Developmental Profile-Behavior Sample. An expressive language aggregate was calculated for each participant at Time 2. A series of correlation and multiple regression models was run to evaluate associations of interest between prelinguistic communication skills as measured at Time 1 and expressive language as measured at Time 2.

resultsVocalization complexity and intentional communication displayed significant zero-order correlations with expressive language across sibling groups. Vocal complexity and responding to joint attention did not have significant added value in predicting later expressive language, after covarying for intentional communication across groups. However, sibling group moderated the association between vocalization complexity and later expressive language, such that vocal complexity displayed incremental validity for predicting later expressive language, covarying for intentional communication, only within Sibs-NA.

conclusionsResults indicate that prelinguistic communication skills, in particular intentional communication, show promise for predicting later expressive language in siblings of autistic children. These findings provide additional empirical support for the notion that early preemptive interventions targeting prelinguistic communication skills, especially intentional communication, may have the potential to scaffold language acquisition and support more optimal language outcomes in this population at high likelihood for a future diagnosis of both autism and language disorder. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.27745437.

Indexed as

Child LanguageCommunicationSiblingsAutistic DisorderChild, PreschoolFemaleHumansInfantLanguage DevelopmentLanguage Development DisordersLanguage TestsMale

Identifiers

PMID39637288
PMCPMC11842043

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.