Evidence map›Paper›PMID 39637038›Full record

SynthesisPloS one2024

Effects of triple semicircular canal plugging on hearing in patients with Meniere's disease: A systematic review and meta-analysis.

Jia Quan Zhu, Li Li Kang, Xiao Dong Wen, Jing Xiao, Yu Jie Li, Rong Li, Hong Jun Liu, Hong Juan Wang, Fu Yu Qiao, Dongbao Yang and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Efficacy analysis of semicircular canal occlusion in controlling vertigo episodes in patients with delayed endolymphatic hydrops].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jia Quan ZhuDepartment of Pharmacy, Fengdu General Hospital, Chongqing, China.
Li Li KangDepartment of Tumor Hematology, Fengdu General Hospital, Chongqing, China.
Xiao Dong WenDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Jing XiaoDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Yu Jie LiDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Rong LiDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Hong Jun LiuDepartment of Administration, Fengdu General Hospital, Chongqing, China.
Hong Juan WangDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Fu Yu QiaoDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Dongbao YangDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.
Bin XiangDepartment of Otolaryngology, Fengdu General Hospital, Chongqing, China.ORCID 0009-0000-3392-9367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTriple semicircular canal plugging is effective in controlling vertigo in patients with Meniere's disease, however, whether the rate of causing hearing loss during treatment is still not uniform. This study aimed to evaluate the effects of Triple semicircular canal plugging (TSCP) on hearing in Meniere's disease (MD) patients.

methodsDatabases Reviewed were PubMed, EMBASE, Scopus, Clinical Trials, Web of Science, Cochrane Library, CNKI, Wanfang, and VIP. The study reported on the duration, follow-up time, hearing loss, and vertigo control outcomes in MD patients evaluated by TSCP. Stata 17 software was used for data analysis and assessing the risk of bias.

resultsThis meta-analysis included 367 MD patients from 7 studies. TSCP efficiently alleviated vertigo with a rate of 99% (95% CI: 0.97, 1.00) and had a hearing loss rate of 22% (95% CI: 0.16, 0.28). Subgroup analysis revealed that for hearing loss, the proportion of patients with disease duration more than or less than 12 months was 14% (95% CI: 0.05, 0.26) and 24% (95% CI: 0.19, 0.29), respectively. For vertigo control, the rates were 100% (95% CI: 0.96, 1.00) and 99% (95% CI: 0.97, 1.00), respectively. For hearing loss, the follow-up time of MD patients more than or less than 24 months was 20% (95% CI: 0.07, 0.38) and 23% (95% CI: 0.18, 0.29), respectively. For vertigo control, the rates were 99% (95% CI: 0.95, 1.00) and 99% (95% CI: 0.97, 1.00), respectively. The duration of the disease and follow-up time had no significant impact on hearing loss and vertigo control rates.

conclusionsTSCP was efficient for vertigo control but with a risk of hearing loss. It could be used as a surgical method for hearing preservation in advanced MD patients.

Indexed as

Meniere DiseaseSemicircular CanalsHearingHearing LossHumansTreatment OutcomeVertigo

Identifiers

PMID39637038
PMCPMC11620686

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.