Evidence map›Paper›PMID 39636775›Full record

ArticleJournal of food and drug analysis2024

Characterization of carbon dots from fructus gardeniae (Zhi-zi) and gardenia charcoal (black Zhi-zi) via microwave-assisted extraction.

Hung-Wen Tsai, Nelly Fitri Tampubolon, Tsunghsueh Wu, Mei-Yao Wu, Yang-Wei Lin

Abstract read
In one paragraph

Article in Journal of food and drug analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hung-Wen TsaiDepartment of Chemistry, National Changhua University of Education, 1 Jin-De Road, Changhua City, 50007, Taiwan.
Nelly Fitri TampubolonInternational Program for Master of Science in Materials and Biological Technology, and Science Education, National Changhua University of Education, 1 Jin-De Road, Changhua City, 50007, Taiwan.
Tsunghsueh WuDepartment of Chemistry, University of Wisconsin-Platteville, 1 University Plaza, Platteville, WI, 53818-3099, USA.
Mei-Yao WuSchool of Post-baccalaureate Chinese Medicine, China Medical University, 91, Hsueh-Shih Road, Taichung, 40424, Taiwan.
Yang-Wei LinDepartment of Chemistry, National Changhua University of Education, 1 Jin-De Road, Changhua City, 50007, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We employed a straightforward microwave-assisted extraction technique to investigate the presence of carbon dots (CDs) in Chinese herbal extracts derived from fructus gardeniae and gardenia charcoal, designated as CDs-1 and CDs-2, respectively. The found CDs exhibited unique photoluminescence with quantum yields of 0.95% for CDs-1 and 1.81% for CDs-2, indicating significant potential for bioimaging applications. Both CD types maintain approximately 80% of their fluorescence intensity after 120 min of continuous 365 nm UV exposure, underscoring their stability and suitability for prolonged biological studies. Moreover, antioxidant activity tests showed that CDs-2 have a higher scavenging capacity, with an SC-50 value of 21.7 μg/mL, compared to 35.9 μg/mL for CDs-1, attributed to their higher content of surface functional groups during the extraction procedure. Notably, the results indicated that the carbonization process of fructus gardeniae leads to the formation of CDs, suggesting a potential link between traditional herbal treatments and modern nanotechnology. This research demonstrates that active compounds in Chinese herbal medicine could possess therapeutic properties when adsorbed on the surface of CDs.

Indexed as

CarbonCharcoalDrugs, Chinese HerbalGardeniaMicrowavesAntioxidantsFruitQuantum DotsAntioxidantsCarbonCharcoalDrugs, Chinese Herbal

Identifiers

PMID39636775
PMCPMC11464033

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.