Evidence map›Paper›PMID 39636721›Full record

ArticleTranslational vision science & technology2024

Relating Standardized Automated Perimetry Performed With Stimulus Sizes III and V in Eyes With Field Loss Due to Glaucoma and NAION.

David Szanto, Michael Wall, Luke X Chong, Mark J Kupersmith

Abstract readComparative Study
In one paragraph

Article in Translational vision science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

David SzantoDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Michael WallDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA.
Luke X ChongSchool of Medicine, Deakin University, Geelong, Australia.
Mark J KupersmithDepartments of Neurology, Ophthalmology and Neurosurgery, CNIIC, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

Statistical Unsupervised Learning VF for IIHTT & ONTTR21EY032522 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KUPERSMITH, MARK J · 2021 to 2022
$495k
NEI NIH HHS R21 EY032522
6 · The paper itself

Abstract

Purpose: Standard automated perimetry (SAP) visual field (VF) results are more repeatable using Goldmann stimulus size V (size V) in eyes with moderate/severe deficits due to glaucoma. There are few reports relating VFs using stimulus size V and III, typically used in the clinic for glaucoma, and none for non-arteritic anterior ischemic optic neuropathy (NAION). We hypothesized that we could compare and relate the VFs with both stimuli for glaucoma and NAION. Methods: We utilized 1992 same-day pairs of size III and size V SAP VFs using the 24-2 strategy for eyes with glaucoma or NAION. We explored the optimal threshold to censor the raw sensitivities, prior to calculating age-standardized total deviations (TDs). We determined the mean and standard deviation of the differences among all TD pairs. We computed a line of best fit to determine closeness to the line of unity. Results: The ideal censoring conversion threshold was 21 decibel (dB) for size III and 24 dB for size V. The difference between size V and size III censored (0.0 ± 1.9 dB) and uncensored (0.4 ± 2.6 dB) TD pairings highly correlate with each other (r2 = 0.70, P < 0.001). The line of best fit from these pairings has a slope of 0.92, which is close to that of the line of unity (m = 1). Conclusions: Censoring plus age correction is a valid method of comparison between size III and size V SAP VFs with moderate to severe VF loss due to optic nerve disorders. Translational Relevance: Size III and size V TDs are comparable in clinical practice.

Indexed as

GlaucomaOptic Neuropathy, IschemicVisual FieldsVisual Field TestsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedVision Disorders

Identifiers

PMID39636721
PMCPMC11622156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.