Evidence map›Paper›PMID 39636547›Full record

ArticleEuropean radiology experimental2024

DSA-based perfusion parameters versus TICI score after mechanical thrombectomy in acute ischaemic stroke patients: a congruence analysis.

Sebastian R Reder, Andrea Kronfeld, Sonja Gröschel, Arda Civelek, Klaus Gröschel, Marc A Brockmann, Timo Uphaus, Marianne Hahn, Carolin Brockmann, Ahmed E Othman

Abstract readComparative Study
In one paragraph

Article in European radiology experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Real-time planar angiographic cerebral perfusion imaging.International journal of computer assisted radiology and surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sebastian R RederDepartment of Neuroradiology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany. sebastianreder91@gmail.com.ORCID http://orcid.org/0000-0002-4193-9976
Andrea KronfeldDepartment of Neuroradiology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany.
Sonja GröschelDepartment of Neurology, University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.
Arda CivelekDepartment of Neurology, University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.
Klaus GröschelDepartment of Neurology, University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.
Marc A BrockmannDepartment of Neuroradiology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany.
Timo UphausDepartment of Neurology, University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.
Marianne HahnDepartment of Neurology, University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.
Carolin BrockmannDepartment of Neuroradiology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany.
Ahmed E OthmanDepartment of Neuroradiology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral factors are frequently considered for outcome prediction rin stroke patients. We assessed the value of digital subtraction angiography (DSA)-based brain perfusion measurements after mechanical thrombectomy (MT) for outcome prediction in acute ischaemic stroke.

methodsFrom DSA image data (n = 90; 38 females; age 73.3 ± 13.1 years [mean ± standard deviation]), time-contrast agent (CA) concentration curves were acquired, and maximum slope (MS), time to peak (TTP), and maximum CA concentration (CA

resultsThe comparison of means revealed a linear trend after stratification into TICI classes for CA

conclusionSemi-quantitative evaluation of DSA-based perfusion parameters prior to and after MT is feasible and could enhance the objectivity and comparability of MT outcome prediction. This technique may offer novel approaches in acute ischaemic stroke management and data comparability. RELEVANCE STATEMENT: DSA-based brain perfusion measurements following interventional stroke therapy could allow for an experience-independent assessment of reperfusion success. It demonstrates predictive power at least equivalent to the established methods. This could support a future automated DSA-based brain perfusion measurement method. KEY POINTS: Currently, the evaluation of stroke therapy success is based on the treating physician's experience. The present study introduces an objective semi-quantitative evaluation method. In predicting clinical outcomes, the traditional expert-based and semi-quantitative methods are equivalent.

Indexed as

Angiography, Digital SubtractionIschemic StrokeThrombectomyAgedAged, 80 and overContrast MediaFemaleHumansMaleMiddle AgedTreatment OutcomeContrast MediaAngiography (digital subtraction)Ischemic strokeOutcomePerfusion imagingThrombectomy

Identifiers

PMID39636547
PMCPMC11621293

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.