Evidence map›Paper›PMID 39636519›Full record

ArticleObesity surgery2025

Obesity-Related Kidney Disease in Bariatric Surgery Candidates.

Pedro Reis Pereira, Manuela Almeida, Patrícia Braga, João Pereira, Sofia Pereira, Mário Nora, Marta Guimarães, Jorge Malheiro, La Salete Martins, Mariana P Monteiro and 1 more

Abstract read
In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pedro Reis PereiraDepartment of Nephrology, Unidade Local de Saúde de Santo António, (ULS Santo António), Porto, Portugal. pedroreisper@gmail.com.
Manuela AlmeidaDepartment of Nephrology, Unidade Local de Saúde de Santo António, (ULS Santo António), Porto, Portugal.
Patrícia BragaUnit for Multidisciplinary Research in Biomedicine (UMIB), School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.
João PereiraUnit for Multidisciplinary Research in Biomedicine (UMIB), School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.
Sofia PereiraUnit for Multidisciplinary Research in Biomedicine (UMIB), School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.
Mário NoraGeneral Surgery Department and CRI for the surgical Treatment of Obesity and Metabolic Diseases, ULS Entre o Douro e Vouga, Santa Maria da Feira, Portugal.
Marta GuimarãesUnit for Multidisciplinary Research in Biomedicine (UMIB), School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.
Jorge MalheiroDepartment of Nephrology, Unidade Local de Saúde de Santo António, (ULS Santo António), Porto, Portugal.
La Salete MartinsDepartment of Nephrology, Unidade Local de Saúde de Santo António, (ULS Santo António), Porto, Portugal.
Mariana P MonteiroUnit for Multidisciplinary Research in Biomedicine (UMIB), School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal.
Anabela RodriguesDepartment of Nephrology, Unidade Local de Saúde de Santo António, (ULS Santo António), Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity has a negative impact in kidney health. However, the hallmarks of kidney dysfunction in bariatric surgery candidates are poorly characterized. To address this knowledge gap, we used a propensity score-matched analysis to compare kidney lesion biomarkers in bariatric surgery candidates and living kidney donors.

methodsBariatric surgery candidates attending a single center for obesity treatment were pair-matched for sex and age to potential living kidney transplant donors (PLKD) using a 1:1 nearest-neighbor approach (N = 400, n = 200/group). A 24-h urine collection was used to analyze proteinuria and creatinine clearance.

resultsPatients with obesity (PWO) had higher creatinine clearance when compared to PLKD (143.35 ± 45.50 mL/min vs 133.99 ± 39.06 mL/min, p = 0.03), which was underestimated when correction for body surface area (BSA) was used (creatinine clearance corrected for BSA of 115.25 ± 33.63 mL/min/1.73 m

conclusionHyperfiltration and disproportionate proteinuria are frequent in patients with obesity. Since hyperfiltration can be underestimated by adjusting creatinine clearance for BSA, this should not be used when evaluating kidney function in bariatric surgery candidates.

Indexed as

Bariatric SurgeryCreatinineKidney TransplantationLiving DonorsObesity, MorbidProteinuriaAdultFemaleHumansMaleMiddle AgedPropensity ScoreCreatinineFatty kidneyHyperfiltrationLiving kidney donationObesity-related glomerulopathyProteinuria

Identifiers

PMID39636519
PMCPMC11717886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.