Evidence map›Paper›PMID 39636342›Full record

ArticleSurgery today2025

Serial positron-emission tomography after induction therapy as a predictor of prognostic outcomes for patients with thymic carcinoma.

Yudai Miyashita, Takashi Kanou, Tomomi Isono, Hiroto Ishida, Hideki Nagata, Teiko Sakurai, Kenji Kimura, Eriko Fukui, Toru Kimura, Naoko Ose and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yudai MiyashitaDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Takashi KanouDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan. kanoutakashi0999@yahoo.co.jp.
Tomomi IsonoDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Hiroto IshidaDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Hideki NagataDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Teiko SakuraiDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Kenji KimuraDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Eriko FukuiDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Toru KimuraDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Naoko OseDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, 2-2 Yamada-Oka, Suita, Osaka, 565-0871, Japan.
Yasushi ShintaniDepartment of General Thoracic Surgery, Osaka University Graduate School of Medicine, 2-15 Yamada-Oka, Suita, Osaka, 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the role of

methodsThe subjects of this retrospective study were 18 patients with thymic carcinoma who underwent FDG-PET, before and after induction therapy. We measured the maximum standardized uptake value (SUVmax) of the tumor and analyzed the correlation between the change in SUVmax and pathological response or recurrence.

resultsInduction therapy led to a reduction in both the tumor size and SUVmax in most patients. A strong correlation (Pearson coefficient = 0.90, p < 0.0001) was observed between the changes in tumor size and SUVmax. Although the SUVmax and tumor size showed no association with the pathological response, an SUVmax change > 50% predicted lower recurrence rates (p = 0.03).

conclusionChanges in the SUVmax following induction therapy may serve as a valuable predictor of recurrence in patients with thymic carcinoma. This finding highlights the potential of FDG-PET as a tool for patient monitoring and prognostication of this rare subset of carcinomas. Further studies are warranted to validate these results and standardize the FDG-PET protocols for optimal clinical use.

Indexed as

Induction ChemotherapyPositron-Emission TomographyPositron Emission Tomography Computed TomographyThymomaThymus NeoplasmsAdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedNeoplasm Recurrence, LocalPredictive Value of TestsPrognosisFluorodeoxyglucose F18RadiopharmaceuticalsFDG-PET/CTPathological responseRecurrenceThymic carcinoma

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.