Evidence map›Paper›PMID 39636337›Full record

ArticleThe international journal of cardiovascular imaging2025

The size of myocardial infarction and peri-infarction edema are not major determinants of diastolic impairment after acute myocardial infarction.

Martin G Sundqvist, Dinos Verouhis, Peder Sörensson, Loghman Henareh, Jonas Persson, Nawzad Saleh, Magnus Settergren, Nils Witt, Felix Böhm, John Pernow and 2 more

Abstract read
In one paragraph

Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Martin G SundqvistCardiology Unit, Södersjukhuset, Stockholm, Sweden. martin.sundqvist@ki.se.ORCID http://orcid.org/0000-0003-0934-761X
Dinos VerouhisUnit of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Peder SörenssonUnit of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Loghman HenarehUnit of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Jonas PerssonDivision of Cardiovascular Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Stockholm, Sweden.
Nawzad SalehUnit of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Magnus SettergrenUnit of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Nils WittCardiology Unit, Södersjukhuset, Stockholm, Sweden.
Felix BöhmDivision of Cardiovascular Medicine, Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Stockholm, Sweden.
John PernowUnit of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Per Tornvall *Cardiology Unit, Södersjukhuset, Stockholm, Sweden.
Martin Ugander *Department of Clinical Physiology, Karolinska University Hospital, and Karolinska Institutet, Stockholm, Sweden.

Funding

Swedish Research Council 10857Swedish Research Council for "Knowledge gaps in clinical medicine" 521-2011-404
6 · The paper itself

Abstract

To study the relationship between myocardial infarction size (IS), myocardial edema, and diastolic dysfunction after acute myocardial infarction (MI) both in the acute phase, and in the development of diastolic dysfunction in the follow-up setting. A further purpose is to study diastolic function using a mechanistic model as well as conventional parameters. Patients underwent cardiovascular magnetic resonance (CMR) imaging and echocardiography including mechanistic analysis using the parameterized diastolic filling method within 4-7 days (acute) and 6 months after a first acute anterior MI (n = 74). Linear regression modeling of echocardiographic diastolic parameters using CMR IS with and without inclusion of the myocardium at risk (MAR) and model comparisons with likelihood ratio tests were performed. Diastolic parameters at 6 months follow-up were modelled using final IS. For most parameters there was no association with acute IS, except for deceleration time (R

Indexed as

Anterior Wall Myocardial InfarctionEdema, CardiacMyocardiumST Elevation Myocardial InfarctionVentricular Dysfunction, LeftVentricular Function, LeftAgedDiastoleEchocardiography, DopplerFemaleHumansMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsProspective StudiesCardiac magnetic resonance imagingDiastolic functionEchocardiographyIschemic heart diseaseKinematic analysisMyocardial infarction

Identifiers

PMID39636337
PMCPMC11742324

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.