Evidence map›Paper›PMID 39636326›Full record

ArticleExperimental brain research2024

Grip force release is impaired in parkinson's disease during a force tracking task.

Sara Davidson, Kenneth Learman, Eric Zimmerman, Anson B Rosenfeldt, Jay L Alberts

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental brain research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara DavidsonDepartment of Biomedical Engineering, 9500 Euclid Avenue, ND-20, Cleveland, OH, 44195, USA.ORCID http://orcid.org/0000-0002-6019-3639
Kenneth LearmanYoungstown State University, Youngstown, OH, USA.
Eric ZimmermanDepartment of Biomedical Engineering, 9500 Euclid Avenue, ND-20, Cleveland, OH, 44195, USA.
Anson B RosenfeldtDepartment of Biomedical Engineering, 9500 Euclid Avenue, ND-20, Cleveland, OH, 44195, USA.
Jay L AlbertsDepartment of Biomedical Engineering, 9500 Euclid Avenue, ND-20, Cleveland, OH, 44195, USA. albertj@ccf.org.

Funding

The Cyclical Lower-extremity Exercise for Parkinson's TrialR01NS073717 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI ALBERTS, JAY L. · 2011 to 2023
$4.8M
The impact of exercise on subthalamic nucleus neural activity in Parkinson's diseaseR21NS129147 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI ALBERTS, JAY L. · 2022 to 2023
$443k
FPTR Foundation for Physical Therapy ResearchNIH HHS R21NS129147NINDS NIH HHS R01 NS073717NINDS NIH HHS R21 NS129147
6 · The paper itself

Abstract

The controlled release of grasping forces underlies skilled dexterous interactions with objects. While declines in force generation and maintenance are well documented in people with Parkinson's disease (PwPD), limited data exist related to how PD impacts the motor control of grasping force release. The aim of this project was to determine how PD impacts grip force release relative to the generation and maintenance of force. It was hypothesized that PwPD would exhibit global deficits in force control relative to controls but would perform disproportionately worse during the controlled release of grip force. Ten PwPD and 10 age-matched controls completed a force-tracking paradigm requiring grip force generation, maintenance, and release. Compared to controls, PwPD were less accurate (i.e. less time within target range), had greater error (i.e. greater relative root mean squared error), and had more trial-to-trial variability in error during grip force release. Ongoing studies are examining the potential neural mechanism(s) underlying of force release impairments in PD, and the relationships between PD severity, manual dexterity, and force release declines.

Indexed as

Hand StrengthParkinson DiseasePsychomotor PerformanceAgedFemaleHumansMaleMiddle AgedDexterous functionForce modulationForce releaseGrip forceParkinson’s disease

Identifiers

PMID39636326
PMCPMC13041725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.