Evidence map›Paper›PMID 39636254›Full record

ArticleJournal of bacteriology2024

Bacterial microcompartment utilization in the human commensal

Chania Clare, Jack W Rutter, Alex J H Fedorec, Stefanie Frank, Chris P Barnes

Abstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. IntegrativemSystems · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chania ClareDepartment of Cell and Developmental Biology, University College London, London, England, United Kingdom.ORCID 0000-0002-5788-7453
Jack W RutterDepartment of Cell and Developmental Biology, University College London, London, England, United Kingdom.
Alex J H FedorecDepartment of Cell and Developmental Biology, University College London, London, England, United Kingdom.
Stefanie FrankDepartment of Biochemical Engineering, University College London, London, England, United Kingdom.
Chris P BarnesDepartment of Cell and Developmental Biology, University College London, London, England, United Kingdom.ORCID 0000-0002-9459-1395

Funding

EC | European Research Council (ERC) 770835UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/T008709/1UKRI | Engineering and Physical Sciences Research Council (EPSRC) EP/R013756/1UKRI | Engineering and Physical Sciences Research Council (EPSRC) EP/W004674/1Wellcome TrustWellcome Trust (WT) 209409/Z/17/Z
6 · The paper itself

Abstract

Bacterial microcompartments (BMCs) are self-assembled protein structures often utilized by bacteria as a modular metabolic unit, enabling the catalysis and utilization of less common carbon and nitrogen sources within a self-contained compartment. The IMPORTANCE: The human gut is a complex environment of different bacterial species, nutrient sources, and changing conditions that are essential for human health. An imbalance can allow for the emergence of opportunistic pathogens. Bacterial microcompartments (BMCs) are utilized by bacteria to metabolize less common nutrients, conferring a growth advantage. Although widely studied in enteropathogens, there is limited research on BMC activity in commensal species. We demonstrate the formation of the eut BMC and utilization of ethanolamine as a carbon source in the human gut commensal

Indexed as

Escherichia coliEthanolamineCarbonEscherichia coli ProteinsGastrointestinal MicrobiomeGene Expression Regulation, BacterialHumansSalmonella entericaCarbonEscherichia coli ProteinsEthanolaminebacterial microcompartmentE. coli Nissle 1917ethanolamine catabolismmicrobiome

Identifiers

PMID39636254
PMCPMC7617246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.