Evidence map›Paper›PMID 39636107›Full record

ArticleAntimicrobial agents and chemotherapy2025

Pathogen genomics in healthcare: overcoming barriers to proactive surveillance.

Alexander J Sundermann, Rossana Rosa, Patrick N A Harris, Evan Snitkin, Waleed Javaid, Nicholas M Moore, Mary K Hayden, Krisandra Allen, Kyle Rodino, Sharon J Peacock and 2 more

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  11. Real-Time Genomic Surveillance for Enhanced Healthcare Outbreak Detection and Control: Clinical and Economic Impact.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander J SundermannMicrobial Genomic Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2439-6287
Rossana RosaInfection Prevention and Control Program, Jackson Health System, Miami, Florida, USA.
Patrick N A HarrisCentre for Clinical Research, Faculty of Medicine, The University of Queensland, Herston, Queensland, Australia.ORCID 0000-0002-2895-0345
Evan SnitkinDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-8409-278X
Waleed JavaidDivision of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Nicholas M MooreDepartments of Internal Medicine and Pathology, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0002-9734-8905
Mary K HaydenDepartments of Internal Medicine and Pathology, Rush University Medical Center, Chicago, Illinois, USA.
Krisandra AllenDigital Epidemiology Services Inc, San Francisco, California, USA.
Kyle RodinoDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sharon J PeacockDepartment of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, England, United Kingdom.ORCID 0000-0002-1718-2782
Lilian M AbboInfection Prevention and Control Program, Jackson Health System, Miami, Florida, USA.ORCID 0000-0002-2364-8358
Lee H HarrisonMicrobial Genomic Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

Enhanced Detection System for Healthcare-Associated Transmission of InfectionR01AI127472 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARRISON, LEE H · 2016 to 2025
$7.6M
NIAID NIH HHS R01 AI127472
6 · The paper itself

Abstract

Pathogen genomic surveillance in healthcare has the potential to enhance patient safety by detecting outbreaks earlier, thereby reducing morbidity and mortality. Despite benefits, there are barriers to adoption, including cost, expertise, and lack of standardized methodologies and incentives. This commentary advocates for 1) investment from healthcare payors, public health, and regulatory bodies and 2) additional research on genomic surveillance for improving patient outcomes and reducing infections. Effective implementation will require strategic investment and cross-sector collaboration.

Indexed as

GenomicsDelivery of Health CareHumansPublic Healthgenomic epidemiologyinfection preventionoutbreakssurveillance

Identifiers

PMID39636107
PMCPMC11784250

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.