Evidence map›Paper›PMID 39635938›Full record

ArticleAutism research : official journal of the International Society for Autism Research2025

Cognitive flexibility in autism: How task predictability and sex influence performances.

Adeline Lacroix, Emma Torija, Alexander Logemann, Monica Baciu, Renata Cserjesi, Frédéric Dutheil, Marie Gomot, Martial Mermillod

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Diametrically opposed sex-specific effects of autistic traits on risk-taking in poker.PCN reports : psychiatry and clinical neurosciences · 2026
    Article
  3. Misophonia symptom severity is linked to impaired flexibility and heightened rumination.British journal of psychology (London, England : 1953) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Cognitive flexibility in autism: How task predictability and sex influence performances.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adeline LacroixUniv. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, LPNC, Grenoble, France.ORCID 0000-0001-6990-5949
Emma TorijaUniv. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, LPNC, Grenoble, France.
Alexander LogemannInstitute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.ORCID 0000-0002-4147-1269
Monica BaciuUniv. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, LPNC, Grenoble, France.
Renata CserjesiInstitute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.
Frédéric DutheilUniversité Clermont Auvergne, CNRS, LaPSCo, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Marie GomotUniversité de Tours, INSERM, Imaging Brain and Neuropsychiatry iBraiN U1253, Tours, France.
Martial MermillodUniv. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, LPNC, Grenoble, France.

Funding

CerCog@UGA ANR-15-IDEX-02MIAI@Grenoble Alpes ANR-19-P3IA-0003Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche
6 · The paper itself

Abstract

While cognitive flexibility challenges are frequently reported in autistic individuals, inconsistencies in the findings prompt further investigation into the factors influencing this flexibility. We suggest that unique aspects of the predictive brain in autistic individuals might contribute to these challenges, potentially varying by sex. Our study aimed to test these hypotheses by examining cognitive flexibility under different predictability conditions in a sample including a similar number of males and females. We conducted an online study with 263 adults (127 with an autism diagnosis), where participants completed a flexibility task under varying levels of predictability (unpredictable, moderately predictable, and predictable). Our results indicate that as task predictability increases, performance improves; however, the response time gap between autistic and non-autistic individuals also widens. Moreover, we observe significant differences between autistic males and females, which differ from non-autistic individuals, highlighting the need to consider sex differences in research related to the cognition of autistic individuals. Overall, our findings contribute to a better understanding of cognitive flexibility and sex differences in autism in light of predictive brain theories and suggest avenues for further research.

Indexed as

Autistic DisorderCognitionExecutive FunctionAdolescentAdultCognitive FlexibilityFemaleHumansMaleMiddle AgedReaction TimeSex FactorsYoung Adultautismcognitive flexibilitygender differencespredictive brainsex differences

Identifiers

PMID39635938
PMCPMC11826006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.