Evidence map›Paper›PMID 39635738›Full record

ArticleBJPsych open2024

Clinical and neurocognitive profiles of a combined clinical high risk for psychosis and clinical control sample: latent class analysis.

Miriam Stüble, Frauke Schultze-Lutter, Michael Kaess, Maurizia Franscini, Nina Traber-Walker, Petra Walger, Benno G Schimmelmann, Kai Vogeley, Joseph Kambeitz, Jochen Kindler and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miriam StübleUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, University of Bern, Switzerland; and Graduate School for Health Sciences, University of Bern, Switzerland.ORCID https://orcid.org/0009-0009-1528-7714
Frauke Schultze-LutterUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, University of Bern, Switzerland; Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Germany; and Department of Psychology, Faculty of Psychology, Airlangga University, Indonesia.ORCID https://orcid.org/0000-0003-1956-9574
Michael KaessUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, University of Bern, Switzerland; and Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Germany.ORCID https://orcid.org/0000-0003-0031-7764
Maurizia FransciniDepartment of Child and Adolescent Psychiatry and Psychotherapy, University of Zurich, Switzerland.
Nina Traber-WalkerDepartment of Child and Adolescent Psychiatry and Psychotherapy, University of Zurich, Switzerland.
Petra WalgerDepartment of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Germany.
Benno G SchimmelmannUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, University of Bern, Switzerland; and University Hospital of Child and Adolescent Psychiatry, University Hospital Hamburg-Eppendorf, Germany.
Kai VogeleyDepartment of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany; and Cognitive Neuroscience (INM3), Institute of Neuroscience and Medicine, Research Center Jülich, Germany.
Joseph KambeitzDepartment of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.ORCID https://orcid.org/0000-0002-8988-3959
Jochen KindlerUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, University of Bern, Switzerland.
Chantal MichelUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy Bern, University of Bern, Switzerland.ORCID https://orcid.org/0000-0003-1165-6681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical high-risk (CHR) state for psychosis demonstrates considerable clinical heterogeneity, presenting challenges for clinicians and researchers alike. Basic symptoms, to date, have largely been ignored in explorations of clinical profiles.

aimsWe examined clinical profiles by using a broader spectrum of CHR symptoms, including not only (attenuated) psychotic, but also basic symptoms.

methodPatients (

resultsA three-class model was best fitting the data, whereby basic symptoms best differentiated between the profiles (η

conclusionsOur profiles based on basic and (attenuated) psychotic symptoms provide clinically useful entities by parsing out heterogeneity in clinical presentation. In future, they could guide class-specific intervention.

Indexed as

basic symptomsclinical heterogeneityearly interventionneurocognitionPsychotic symptoms

Identifiers

PMID39635738
PMCPMC11698148

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