Evidence map›Paper›PMID 39635338›Full record

ArticleJournal of clinical medicine research2024

Association Between the Development of Sensorineural Hearing Loss and Blood NAD

Hideaki Sakata, Ken Hayashi, Ryo Matsuyama, Tomoyo Omata, Masanobu Kanou, Kei Yamana, Sho Kanzaki

Abstract read
In one paragraph

Article in Journal of clinical medicine research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Pathophysiologic phenotyping of idiopathic sudden sensorineural hearing loss: toward precision management.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hideaki SakataKawagoe Ear Institute, Division of Otorhinolaryngology, Kawagoe Mine Medical Center, Kawagoe City, Saitama 350-1122, Japan.ORCID https://orcid.org/0000-0003-4354-801X
Ken HayashiKawagoe Ear Institute, Division of Otorhinolaryngology, Kawagoe Mine Medical Center, Kawagoe City, Saitama 350-1122, Japan.
Ryo MatsuyamaNutraceutical Group, New Business Development Unit, Teijin Limited, Hino, Tokyo, Japan.
Tomoyo OmataDiscovery DMPK Research Group, Toxicology & DMPK Research Department, Teijin Institute for Bio-Medical Research, Teijin Pharma Limited, Hino, Tokyo, Japan.
Masanobu KanouNutraceutical Group, New Business Development Unit, Teijin Limited, Hino, Tokyo, Japan.
Kei YamanaNutraceutical Group, New Business Development Unit, Teijin Limited, Hino, Tokyo, Japan.
Sho KanzakiDivision of Auditory Disorders, National Institute of Sensory Organ, National Hospital Organization of Tokyo Medical Center, Meguro Ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hearing loss prevalence increases with age, affecting over 25% of the global population aged 60 years or older. The aim of the study was to investigate the association between the development of sensorineural hearing loss (SNHL) and the blood levels of nicotinamide adenine dinucleotide (NAD Methods: A single-center, observational study was conducted at Kawagoe Otology Institute in Japan. A total of 80 patients were included and allocated to four groups of 20 patients each: patients aged 50 - 79 years with or without unilateral sudden sensorineural hearing loss (SSNHL), and patients aged ≥ 80 years with or without bilateral age-related hearing loss (ARHL). The distribution of whole-blood NAD Results: Comparison of NAD Conclusions: Decreased amount of NAD

Indexed as

AgingMitochondrionNicotinamide adenine dinucleotideSensorineural hearing lossSirtuin 1

Identifiers

PMID39635338
PMCPMC11614409

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.