ArticleInfection and drug resistance2024
Acute Pancreatitis and Leukemoid Reaction as the Presenting Manifestation of Hemorrhagic Fever with Renal Syndrome: A Case Report.
Article in Infection and drug resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Spectrum of Gastrointestinal, Hepatobiliary, and Pancreatic Involvement in Hantavirus Infection: A Narrative Review.Cureus · 2026Review
- Clinical and laboratory factors associated with scrub typhus and hemorrhagic fever with renal syndrome in Southwestern Korea: A cross-sectional study.PLoS neglected tropical diseases · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hemorrhagic fever with renal syndrome (HFRS), caused by Orthohantavirus hantanense (HTNV) infection, is characterized by a range of symptom including fever, hemorrhage, and renal impairment. Acute pancreatitis and leukemoid reaction associated with HFRS have been less frequently reported. Case Presentation: A 20-year-old male presented with fever, dizziness, and gastrointestinal symptom, which progressed to acute pancreatitis and leukemoid reaction. Despite initial treatment, his condition worsened, necessitating transfer to a tertiary care facility. Upon admission, the patient exhibited signs of organ dysfunction, and laboratory tests confirmed leukocytosis and thrombocytopenia, with imaging suggestive of pancreatitis. HTNV antibody test results were positive. Discussion: This case illustrates the complexity of diagnosing HFRS when the disease presents atypically. The symptom that are shared with other conditions can lead to misdiagnosis. Treatment of HFRS patients requires a multidisciplinary approach, with particular attention to the timing and type of therapy to manage complications effectively. Conclusion: This report emphasizes the importance of recognizing atypical presentations of HFRS and the benefits of a prompt and comprehensive treatment strategy. Early diagnosis and a tailored therapeutic approach are crucial for improving patient outcomes in such rare and complex cases. The case underscores the necessity for clinicians to be vigilant for secondary symptom of HFRS, particularly in high-incidence regions, and the role of early diagnosis and treatment in improving outcomes.
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