Evidence map›Paper›PMID 39634909›Full record

ArticlePakistan journal of medical sciences2024

Correlation between serum levels of cyclooxygenase-2, aquaporin-1, pepsinogen I, gastrin-17 and pathological features of Laryngeal Cancer.

Danping Li, Xiaoqiong Qian, Cong Li, Song Shi

Abstract read
In one paragraph

Article in Pakistan journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Danping LiDanping Li, Department of Otorhinolaryngology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 111 Xianxia Road, Shanghai, 200336, P.R. China.
Xiaoqiong QianXiaoqiong Qian, Department of Otorhinolaryngology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 111 Xianxia Road, Shanghai, 200336, P.R. China.
Cong LiCong Li, Department of Otorhinolaryngology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 111 Xianxia Road, Shanghai, 200336, P.R. China.
Song ShiSong Shi, Department of Otorhinolaryngology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 111 Xianxia Road, Shanghai, 200336, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the association between the levels of cyclooxygenase-2 (COX-2), aquaporin-1 (AQP1), pepsinogen I (PGI), and gastrin-17 (G17) and pathological features of laryngeal cancer (LC). Methods: Clinical data of 120 patients with LC, treated in Shanghai Jiao Tong University School of Medicine from May 2022 to May 2023, as well as 120 healthy individuals who underwent physical examinations during the same period, were retrospectively analyzed. Serum levels of COX-2, AQP1, PGI, and G17 of LC patients and the healthy cohort were compared, and their association with pathological features of LC was investigated. Results: LC was associated with significantly higher serum levels of COX-2, AQP1, and G17 and lower of PGI compared to the control group ( Conclusions: Levels of COX-2, AQP1, PGI, and G17 showed significant association with specific pathological features of LC. Serum levels of COX-2, AQP1, PGI, and G17 have certain predictive value for LC, and the combined predictive value of these four indicators is higher than that of a single indicator.

Indexed as

Aquaporin-1Cyclooxygenase-2Gastrin-17Laryngeal cancerPepsinogen I

Identifiers

PMID39634909
PMCPMC11613371

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.