Evidence map›Paper›PMID 39634380›Full record

ArticleGenetics in medicine open2024

Factors affecting couples' decision making about expanded prenatal cell-free DNA screening.

Kelsey Mumford, Saskia Hendriks, Skye Miner, Chloe O Huelsnitz, Paul Wakim, Benjamin E Berkman

Abstract read
In one paragraph

Article in Genetics in medicine open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelsey MumfordNational Institutes of Health Department of Bioethics, Bethesda, MD.ORCID 0000-0003-0594-2454
Saskia HendriksNational Institutes of Health Department of Bioethics, Bethesda, MD.ORCID 0000-0003-3574-2306
Skye MinerRAND Corporation, Boston, MA.ORCID 0000-0002-8848-2440
Chloe O HuelsnitzNational Cancer Institute Division of Cancer Control and Population Sciences, Bethesda, MD.
Paul WakimNational Institutes of Health Clinical Center Biostatistics and Clinical Epidemiology Service, Bethesda, MD.ORCID 0000-0002-5951-0983
Benjamin E BerkmanNational Institutes of Health Department of Bioethics, Bethesda, MD.ORCID 0000-0002-9098-0799

Funding

Intramural NIH HHS Z99 HG999999
6 · The paper itself

Abstract

Purpose: To assess intended parents' preferences about expanded prenatal cell-free DNA screening. Methods: A survey was administered to couples who were pregnant or trying to conceive. Partners within couples were independently asked about willingness to seek prenatal cell-free DNA screening for diseases and traits that varied by severity, treatability, age of onset, and reliability. Additional questions explored couples' decision-making processes and how various factors would affect those decisions. Results: Respondents ( Conclusion: These data suggest that couples are highly information seeking when presented with all testing options neutrally, but most desire to be presented with firm testing recommendations from their clinician.

Indexed as

BioethicscfDNAPrenatal testing

Identifiers

PMID39634380
PMCPMC11613822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.