Evidence map›Paper›PMID 39634328›Full record

ArticleKidney medicine2024

Insulin Resistance in Hypercalciuric Calcium Kidney Stone Patients.

Megan Prochaska, Gloria Adeola, Noah Vetter, Raghavendra G Mirmira, Fredric Coe, Elaine Worcester

Abstract read
In one paragraph

Article in Kidney medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Association of Estimated Glucose Disposal Rate With Prevalent Kidney Stones: A Large-Scale Cross-Sectional Study in China.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Megan ProchaskaDepartment of Medicine, University of Chicago, Chicago IL.
Gloria AdeolaDepartment of Medicine, University of Chicago, Chicago IL.
Noah VetterDepartment of Medicine, University of Chicago, Chicago IL.
Raghavendra G MirmiraDepartment of Medicine, University of Chicago, Chicago IL.
Fredric CoeDepartment of Medicine, University of Chicago, Chicago IL.
Elaine WorcesterDepartment of Medicine, University of Chicago, Chicago IL.

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI GRAEME I BELL · 2013 to 2026
$20.9M
Mechanisms of disordered citrate and oxalate excretion in nephrolithiasisK23DK127252 · NIDDK · UNIVERSITY OF CHICAGO · PI PROCHASKA, MEGAN L · 2022 to 2025
$744k
NIDDK NIH HHS K23 DK127252NIDDK NIH HHS P30 DK020595
6 · The paper itself

Abstract

Rational & Objective: Diabetes and uric acid kidney stones are strongly associated. Patients with calcium kidney stones also have higher risk of developing diabetes compared with nonkidney stone patients yet this has not been further investigated. We aimed to characterize insulin resistance in calcium kidney stone patients. Study Design: Observational. Setting & Population: This study was performed in the University of Chicago Clinical Research Center. Kidney stone patients (N = 42) were selected for having idiopathic hypercalciuria and calcium stones with no other medical conditions, and controls (N = 27) were healthy. Exposures: All participants presented to the Clinical Research Center in a fasting state and at least 2 timed fasting blood and urine collections were collected before a fixed breakfast. Six additional timed blood and urine collections were performed after breakfast. Outcomes: We compared fasting and fed indices of insulin resistance between the groups. Analytic Approach: We used Results: In separate multivariable linear models, kidney stone patients had higher fasting serum insulin levels (24 (3-46 pmol/L), Limitations: Single institution. Small sample size limited subanalyses by different calcium stone types. Conclusions: Calcium kidney stone patients without diabetes or other medical conditions demonstrated signs of insulin resistance compared with healthy matched controls.

Indexed as

Insulin resistancekidney stonesnephrolithiasisurine calcium

Identifiers

PMID39634328
PMCPMC11615144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.