Evidence map›Paper›PMID 39634326›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2024

Comparison of sequential multi-detector CT and cone-beam CT perfusion maps in 39 subjects with anterior circulation acute ischemic stroke due to a large vessel occlusion.

John W Garrett, Kelly Capel, Laura Eisenmenger, Azam Ahmed, David Niemann, Yinsheng Li, Ke Li, Dalton Griner, Sebastian Schafer, Charles Strother and 2 more

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

John W GarrettUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0002-8152-736X
Kelly CapelUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.
Laura EisenmengerUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0001-6764-4239
Azam AhmedUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Neurosurgery, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0001-7293-496X
David NiemannUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Neurosurgery, Madison, Wisconsin, United States.
Yinsheng LiUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Medical Physics, Madison, Wisconsin, United States.
Ke LiUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0002-2672-2672
Dalton GrinerUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Medical Physics, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0001-7673-5140
Sebastian SchaferSiemens Healthineers AG, Varian Cancer Therapy Systems, Forchheim, Germany.ORCID https://orcid.org/0000-0002-6989-5215
Charles StrotherUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0002-4235-8081
Guang-Hong ChenUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0002-2263-1028
Beverly Aagaard-KienitzUniversity of Wisconsin in Madison, School of Medicine and Public Health, Department of Radiology, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0002-3609-9394

Funding

One Stop Shop Imaging for Acute Ischemic StrokeTreatmentU01EB021183 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI CHEN, GUANG-HONG · 2015 to 2020
$3.5M
Next Generation Cone Beam CT with Improved Contrast Resolution and Added Spectral Imaging FunctionalityR01EB034011 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI Guang-Hong Chen · 2023 to 2026
$2.3M
NIBIB NIH HHS R01 EB034011NIBIB NIH HHS U01 EB021183
6 · The paper itself

Abstract

Purpose: The critical time between stroke onset and treatment was targeted for reduction by integrating physiological imaging into the angiography suite, potentially improving clinical outcomes. The evaluation was conducted to compare C-Arm cone beam CT perfusion (CBCTP) with multi-detector CT perfusion (MDCTP) in patients with acute ischemic stroke (AIS). Approach: Thirty-nine patients with anterior circulation AIS underwent both MDCTP and CBCTP. Imaging results were compared using an in-house algorithm for CBCTP map generation and RAPID for post-processing. Blinded neuroradiologists assessed images for quality, diagnostic utility, and treatment decision support, with non-inferiority analysis (two one-sided tests for equivalence) and inter-reviewer consistency (Cohen's kappa). Results: The mean time from MDCTP to angiography suite arrival was Conclusions: In this small paper, CBCTP was noninferior to MDCTP, potentially saving nearly an hour per patient if they went directly to the angiography suite upon hospital arrival.

Indexed as

cone beam CTCT perfusionendovascular therapystrokethrombectomy

Identifiers

PMID39634326
PMCPMC11614149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.