Evidence map›Paper›PMID 39634225›Full record

ArticleACS central science2024

Overcoming the Limitations of Transition-Metal Catalysis in the Chemoenzymatic Dynamic Kinetic Resolution (DKR) of Atropisomeric Bisnaphthols.

Kun Wang, Wei Wang, Dingkai Lou, Jie Zhang, Changli Chi, Jan-E Bäckvall, Xiang Sheng, Can Zhu

Abstract read
In one paragraph

Article in ACS central science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kun WangDepartment of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, P.R. China.
Wei WangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, P.R. China.
Dingkai LouDepartment of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, P.R. China.
Jie ZhangDepartment of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, P.R. China.
Changli ChiDepartment of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, P.R. China.
Jan-E BäckvallDepartment of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.ORCID https://orcid.org/0000-0001-8462-4176
Xiang ShengTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, P.R. China.ORCID https://orcid.org/0000-0002-6542-6649
Can ZhuDepartment of Chemistry, Fudan University, 2005 Songhu Road, Shanghai 200438, P.R. China.ORCID https://orcid.org/0000-0001-6604-6173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemoenzymatic dynamic kinetic resolution (DKR), combining a metal racemization catalyst with an enzyme, has emerged as an elegant solution to transform racemic substrates into enantiopure products, while compatibility of dual catalysis is the key issue. Conventional solutions have utilized presynthesized metal complexes with a fixed and bulky ligand to protect the metal from the enzyme system; however, this has been generally limited to anionic ligands. Herein, we report our strategy to solve the compatibility issue by employing a reliable ligand that firmly coordinates

Identifiers

PMID39634225
PMCPMC11613327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.