Interplay between lipid profile and anthropometric measures as indicators of cardiometabolic risk in women with polycystic ovary syndrome.

Objectives: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that often coexists with cardiometabolic risk factors. Women with PCOS have a two-fold increased risk of developing type 2 diabetes and substantially elevated risk for cardiovascular disease (CVD) events later in life. PCOS patients may require more comprehensive metabolic screening to identify populations at higher risk of developing CVD and dyslipidemia. It is recommended to evaluate lipid profile, glucose tolerance and of women with PCOS every 2-3 years. Simple, short, and easy methods for the assessment of CVD risk in women with PCOS may be useful tools for implementing CVD prevention strategies by doctors or nutritionists. The aim of this study was to investigate the usefulness of anthropometric indices in the assessment of cardiometabolic risk based on lipid profile in patients with PCOS. Material and methods: The study involved 49 of Caucasian women aged 18-39 who were diagnosed with PCOS based on the Rotterdam criteria and divided into two groups with normal lipid profile (N=14) and dyslipidemia (N=35). Biochemical parameters were tested in the morning while fasting. Anthropometric parameters such as Body Mass Index (BMI), Body Adiposity Index (BAI), Waist-to-Hip Ratio (WHR), and Waist-to-Height Ratio (WHtR) were calculated, while the Percent of Body Fat was measured using a body analyzer. Results: The study demonstrated that women with dyslipidemia were older than the control group, 33 years (27-37) Conclusions: Analysis of simple and rapid parameters used to assess body fat, such as BMI, BAI, WHR, and WHtR, has shown that they are poor predictors of dyslipidemia in women with PCOS. In young women with PCOS, age appears to be a more reliable predictor of dyslipidemia.