Evidence map›Paper›PMID 39634144›Full record

ArticleNanophotonics (Berlin, Germany)2023

Label-free, ultra-low detection limit DNA biosensor using high quality optical microcavity functionalized by DNA tetrahedral nanostructure probes.

Hongdan Wan, Shuai Zhang, Yu Gu, Jinxin Xiong, Ji Xu, Cheng Wan, Jie Chao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanophotonics (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hongdan WanNanjing University of Posts and Telecommunications, #9 Wenyuan Road, Nanjing, 210000, China.ORCID https://orcid.org/0000-0003-4179-7397
Shuai ZhangNanjing University of Posts and Telecommunications, #9 Wenyuan Road, Nanjing, 210000, China.
Yu GuNanjing University of Posts and Telecommunications, #9 Wenyuan Road, Nanjing, 210000, China.
Jinxin XiongNanjing University of Posts and Telecommunications, #9 Wenyuan Road, Nanjing, 210000, China.
Ji XuNanjing University of Posts and Telecommunications, #9 Wenyuan Road, Nanjing, 210000, China.
Cheng WanSuzhou Yikon Medical Laboratory Company Ltd., Xukang Medical·Yikon Genomics, Suzhou 215000, China.
Jie ChaoNanjing University of Posts and Telecommunications, #9 Wenyuan Road, Nanjing, 210000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study proposes and demonstrates a novel label-free DNA biosensor using high quality optical microcavity functionalized by 3D DNA nanostructure probes. To achieve ultra-low limit DNA biosensing, optical sensing interface of the hollow-core, thin wall-thickness microcavity was functionalized by self-assembled DNA tetrahedral nanostructure (DTN) probes with size of 17 bp and length of ∼5.8 nm. High efficiency binding of the DTN probes with the optical sensor interface and the target ssDNA are achieved. Whispering gallery mode (WGM) spectra with high-

Indexed as

DNA tetrahedral nanostructure probeslabel-freelimit of detectionsingle-nucleotide mismatch recognitionsurface functionalizationwhispering gallery mode

Identifiers

PMID39634144
PMCPMC11501935

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.