Evidence map›Paper›PMID 39634069›Full record

ArticleFrontiers in plant science2024

LAZARUS 1 functions as a positive regulator of plant immunity and systemic acquired resistance.

Yue Chen, Yue Han, Weijie Huang, Yanjun Zhang, Xiaoli Chen, Dongyue Li, Yi Hong, Huhu Gao, Kewei Zhang, Yuelin Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in plant science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Roles of maizeFrontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yue ChenShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Yue HanShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Weijie HuangDepartment of Botany, University of British Columbia, Vancouver, BC, Canada.
Yanjun ZhangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, Zhejiang, China.
Xiaoli ChenShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Dongyue LiShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Yi HongShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Huhu GaoShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.
Kewei ZhangZhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants, College of Life Sciences, Zhejiang Normal University, Jinhua, Zhejiang, China.
Yuelin ZhangKey Laboratory of Bio-resource and Eco-environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China.
Tongjun SunShenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic acquired resistance (SAR) is activated by local infection and confers enhanced resistance against subsequent pathogen invasion. Salicylic acid (SA) and N-hydroxypipecolic acid (NHP) are two key signaling molecules in SAR and their levels accumulate during SAR activation. Two members of plant-specific Calmodulin-Binding Protein 60 (CBP60) transcription factor family, CBP60g and SARD1, regulate the expression of biosynthetic genes of SA and NHP. CBP60g and SARD1 function as master regulators of plant immunity and their expression levels are tightly controlled. Although there are numerous reports on regulation of their expression, the specific mechanisms by which SARD1 and CBP60g respond to pathogen infection are not yet fully understood. This study identifies and characterizes the role of the LAZARUS 1 (LAZ1) and its homolog LAZ1H1 in plant immunity. A forward genetic screen was conducted in the

Indexed as

CBP60gLAZ1N-hydroxypipecolic acidsalicylic acidSARD1

Identifiers

PMID39634069
PMCPMC11614604

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.