ArticleHealth science reports2024
Risk Evaluation and Mitigation Strategies for Potential Outbreaks of Nipah Virus Infection: Evidenced by the Recent Incidences in Southeast Asian Countries.
Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Assessing the pandemic potential of Nipah virus: From molecular pathogenesis to ecological spillover risks.Infectious medicine · 2026Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The importance of studying Nipah virus (NiV) stems from its high fatality rates and potential for causing widespread outbreaks. Recent incidences in Southeast Asian countries highlight the urgent need for effective risk evaluation and mitigation strategies. Justification: Studying NiV in Southeast Asia is crucial due to the geographic and epidemiological significance that makes this region predominantly susceptible to the virus. Objectives: This study aims to identify the risk factors of NiV, evaluate current mitigation strategies, and suggest improvements against this virus. Methods: This review incorporates articles from the PubMed database related to available NiV treatments, vaccines, mitigation strategies, transmission data, and mortality to comprise an extensive analysis of pertinent information. Findings: NiV warrants international attention, due to the high mortality rate and the rising number of human-to-human transmission vectors. NiV is difficult to diagnose early on in the infection due to its generic symptoms, and the two strains of NiV (B and M), pose significant challenges to healthcare institutions. Vaccines, such as the VSV-stored, virus-like particle-based, and mRNA-based NiV show promising results in both animal and human studies. Synthetic medicines, like Ribavirin, and favipiravir showed promising results in NiV-infected patients. Therapeutic infectious particles increased survival from 10% to roughly 70%-80% in animals. Phytochemicals, like serpentine and neoandrographolide are alternatives to NiV-G ligands. Griffithsin, an algae derivative has also shown efficacy in treating NiV infections. Artificial intelligence determines the NiV infection with an accuracy of 88.3%. Conclusions: The strategies to control NiV must be one of a One Health approach, incorporating environmental and social factors. Extensive research on vaccines that showed promising results in animals needs to be tested for humans on a large scale. The major mitigation strategy available is the public awareness during the outbreak about NiV transmission vectors, quarantine protocol, and food hygiene.
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