Evidence map›Paper›PMID 39633646›Full record

ReviewFrontiers in physiology2024

Basic research and opportunities for translational advancement in the field of mammalian ∼12-hour ultradian chronobiology.

William Dion, Bokai Zhu

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William DionAging Institute of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Bokai ZhuAging Institute of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Funding

Nuclear speckle liquid-liquid phase separation dynamics in senescence and agingF31AG080998 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DION, WILLIAM AARON · 2023 to 2025
$117k
NIA NIH HHS F31 AG080998
6 · The paper itself

Abstract

Repetitive variations, such as oscillation, are ubiquitous in biology. In this mini review, we present a general summary of the ∼24 h circadian clock and provide a fundamental overview of another biological timekeeper that maintains ∼12 h oscillations. This ∼12 h oscillator is proposed to function independently of the circadian clock to regulate ultradian biological rhythms relevant to both protein homeostasis and liver health. Recent studies exploring these ∼12 h rhythms in humans are discussed, followed by our proposal that mammary gland physiology represents a promising area for further research. We conclude by highlighting potential translational applications in ∼12 h ultradian chronobiology.

Indexed as

circadian rhythmNAFLD/MAFLDnuclear specklesproteostasisultradian rhythmunfolded protein responseXBP1s

Identifiers

PMID39633646
PMCPMC11614809

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.