Evidence map›Paper›PMID 39633336›Full record

ArticleBMC psychiatry2024

Clinical heterogeneity of feeding and eating disorders: using personality psychopathology to differentiate "simplex" and "complex" phenotypes.

Marco Colizzi, Carla Comacchio, Marco Garzitto, Lavinia Bucciarelli, Anna Candolo, Maddalena Cesco, Veronica Croccia, Alessandra Ferreghini, Rosita Martinelli, Alessandra Nicotra and 2 more

Abstract read
In one paragraph

Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marco ColizziUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy. marco.colizzi@uniud.it.
Carla ComacchioUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Marco GarzittoUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Lavinia BucciarelliUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Anna CandoloUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Maddalena CescoUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Veronica CrocciaUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Alessandra FerreghiniUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Rosita MartinelliUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Alessandra NicotraUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Giulia SebastianuttoUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.
Matteo BalestrieriUnit of Psychiatry and Eating Disorders, Department of Medicine (DMED), University of Udine, Udine, 33100, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate Feeding and Eating Disorders (FED) heterogeneity based on the co-occurrence of FED symptoms and personality psychopathology, on the hypothesis that empirical profiles would not confirm current FED categories but identify unique phenotypes carrying different levels of clinical complexity.

methodsLatent Profile Analysis profiled FED patients based on the assessment of both FED symptoms, through the Eating Disorders Inventory, third version (EDI-3), and personality characteristics, through the Minnesota Multiphasic Personality Inventory-2. Then, profiles were compared across socio-demographic and clinical characteristics.

resultsAmong 109 eligible patients, three FED profiles were identified: (i) FED simplex (low eating symptoms, absence of dysfunctional personality); (ii) FED simplex-severe (high eating symptoms only); and (iii) FED complex-severe (high eating symptoms and dysfunctional personality). Despite an uneven distribution (χ

conclusionsFindings support the hypothesis of distinguishing FED simplex and complex phenotypes, based on the co-occurrence of dysfunctional personality, with implications for FED severity and clinical practice.

Indexed as

Feeding and Eating DisordersPhenotypeAdolescentAdultBody Mass IndexFemaleHumansMaleMMPIPersonalityPersonality DisordersYoung AdultAnorexia NervosaAnxiety DisorderBinge Eating DisorderBody Mass IndexBulimia NervosaDuration of Untreated IllnessMental HealthObsessive–Compulsive DisorderPersonality PsychopathologySymptom clusters

Identifiers

PMID39633336
PMCPMC11616308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.