Evidence map›Paper›PMID 39633105›Full record

Trial reportJournal of general internal medicine2025

Automated Text Message-Based Program to Improve Uncontrolled Blood Pressure in Primary Care Patients: A Randomized Clinical Trial.

Eric Bressman, Klea Profka, Laurie Norton, Kayla Clark, Katy Mahraj, Zakiya Walker, Leslie Reid-Bey, Anthony Girard, Charles Rareshide, Lin Xu and 4 more

Registry-linked trialAbstract readMulticenter StudyPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05571410 (Program Design Hypertension Chat Bot Pilot Study With the Primary Care Service Line), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05571410 nacompletednot on this map

Program Design Hypertension Chat Bot Pilot Study With the Primary Care Service Line

TypeinterventionalSponsorUniversity of PennsylvaniaRan2023 to 2023Enrolled300ConditionsHypertensionArmsHTN Chat bot
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eric BressmanDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. eric.bressman@pennmedicine.upenn.edu.ORCID 0000-0003-4688-0747
Klea ProfkaCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Laurie NortonCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Kayla ClarkCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Katy MahrajCenter for Health Care Transformation and Innovation, University of Pennsylvania Health System, Philadelphia, PA, USA.
Zakiya WalkerCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Leslie Reid-BeyCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Anthony GirardLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.
Charles RareshideCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Lin XuCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Jingsan ZhuCenter for Health Incentives and Behavioral Economics, University of Pennsylvania Health System, Philadelphia, PA, USA.
Mary PuttDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kevin G VolppLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.
Anna U MorganDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
NCATS NIH HHS UL1 TR001878NCATS NIH HHS UL1TR001878
6 · The paper itself

Abstract

backgroundSuboptimal control of BP is common, although safe and effective treatments are widely available. Conventional management relies on office visits, but this can be an inefficient path to medication optimization.

objectiveTo assess the effectiveness of an intensive, 6-month remote BP management program among patients with uncontrolled hypertension.

designA two-arm randomized clinical trial which ran from January to July 2023 at two primary care practices with an in-clinic BP measurement at the end of the intervention.

participantsEstablished adult patients (ages 21-80) of study practices with uncontrolled hypertension (two measurements > 140/90 in the prior 12 months) and an active prescription for at least one anti-hypertensive agent.

interventionParticipants received automated text messages prompting them to check their BP weekly for 6 months. An RN and APP monitored BP data entered by the participant. The automated platform escalated any out-of-normal range readings or needs to the program staff. MAIN MEASURES: The primary outcome was change in SBP from baseline to the end-of-study measurement. Enrollment and engagement measures were collected for the intervention arm. KEY

resultsOf the 300 participants, the mean (SD) age was 63 (± 12.2) years; 133 (44.3%) were male and 167 (55.7%) were female; 154 (51.5%) self-identified as Black and 120 (40.1%) White; and 119 (39.7%) were insured by Medicare and 41 (13.7%) by Medicaid. The change in SBP at 6 months among those who completed the end-of-study measurement was - 14.66 mmHg (95% CI - 19.95, - 9.36) in the intervention arm and - 10.87 mmHg (95% CI - 18.04, - 3.69) in the control arm (p = 0.39). Within the intervention arm, 97 participants (64.7%) completed all enrollment steps, and these participants submitted BPs 72.8% of the weeks. Participants in the intervention arm had a greater number of medication changes (0.81 vs 0.57 in the control arm, p = 0.01) over the study period.

conclusionsIn this randomized clinical trial of a 6-month automated text messaging program, there was no significant difference in the change in SBP among participants in each arm.

trial registrationClinicalTrials.gov Identifier: NCT05571410.

Indexed as

Blood PressureHypertensionText MessagingAdultAgedAged, 80 and overAntihypertensive AgentsFemaleHumansMaleMiddle AgedPilot ProjectsPrimary Health CareYoung AdultAntihypertensive Agents

Identifiers

PMID39633105
PMCPMC12045849

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.