Evidence map›Paper›PMID 39632962›Full record

ArticleScientific reports2024

Oxidative stress-induced cytotoxicity of HCC2998 colon carcinoma cells by ZnO nanoparticles synthesized from Calophyllum teysmannii.

Hemaroopini Subramaniam, Chan Kiang Lim, Lai Hock Tey, Ling Shing Wong, Sinouvassane Djearamane

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  7. Multifunctional hierarchical NiScientific reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hemaroopini SubramaniamDepartment of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Jalan Universiti, Bandar Barat, Kampar, Perak, 31900, Malaysia.
Chan Kiang LimDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Jalan Universiti, Bandar Barat, Kampar, Perak, 31900, Malaysia.
Lai Hock TeyDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Jalan Universiti, Bandar Barat, Kampar, Perak, 31900, Malaysia.
Ling Shing WongLife Science Division, Faculty of Health and Life Sciences, INTI International University, Nilai, 71800, Malaysia.
Sinouvassane DjearamaneDepartment of Allied Health Sciences, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Jalan Universiti, Bandar Barat, Kampar, Perak, 31900, Malaysia. sinouvassane@utar.edu.my.

Funding

Universiti Tunku Abdul Rahman UTAR Research Fund 6200/SB7
6 · The paper itself

Abstract

The field of green synthesis, namely using plant extracts for the production of metal nanoparticles, is rapidly gaining traction. Therefore, this study investigated the process of producing zinc oxide nanoparticles (ZnO NPs) using a water-based extract derived from the stem bark of Calophyllum teysmannii. Notably, this is the first documented utilization of this particular plant source. The presence of a distinct Ultraviolet-Visible (UV-Vis) absorption peak at 372 nm provided evidence for the creation of ZnO nanoparticles. The X-ray Diffractometer (XRD) and Field Emission Scanning Electron Microscopy (FESEM) investigations indicated that the nanoparticles exhibited sizes ranging from 31.5 to 59.9 nm and had spherical morphologies. Energy Dispersive X-ray Diffractometer (EDX) analysis verified the elemental composition of the ZnO nanoparticles, whereas the Fourier Transform Infrared (FTIR) spectra showed clear peaks, demonstrating their production. The FTIR examination of the C. teysmannii extract revealed peaks at around 3370 cm

Indexed as

CalophyllumMetal NanoparticlesOxidative StressPlant ExtractsZinc OxideAnimalsCell Line, TumorCell SurvivalChlorocebus aethiopsColonic NeoplasmsHumansVero CellsPlant ExtractsZinc OxideCalophyllumCytotoxicityGreen synthesisOxidative stressZinc oxide nanoparticles

Identifiers

PMID39632962
PMCPMC11618351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.