Evidence map›Paper›PMID 39632850›Full record

ArticleNature communications2024

Bioinspired adaptive lipid-integrated bilayer coating for enhancing dynamic water retention in hydrogel-based flexible sensors.

Ming Bai, Yanru Chen, Liyang Zhu, Ying Li, Tingting Ma, Yiran Li, Meng Qin, Wei Wang, Yi Cao, Bin Xue

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Robust Stitching Interface and Deep Learning Empowered Hydrogel Human-Machine Interface.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Smart Hydrogels in Wearable Electronics for Wound Treatments.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  13. Gel-Based Ionic Circuits.Chemical reviews · 2025
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ming BaiCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China.
Yanru ChenCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China.
Liyang ZhuCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China.
Ying LiInstitute of Advanced Materials and Flexible Electronics (IAMFE), School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, 219 Ningliu road, Nanjing, China.ORCID 0000-0003-3898-698X
Tingting MaCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China.
Yiran LiCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China.ORCID 0000-0001-7922-7766
Meng QinCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China.
Wei WangCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China. wangwei@nju.edu.cn.ORCID 0000-0001-5441-0302
Yi CaoCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China. caoyi@nju.edu.cn.ORCID 0000-0003-1493-7868
Bin XueCollaborative Innovation Center of Advanced Microstructures, National Laboratory of Solid State Microstructure, Department of Physics, Nanjing University, Nanjing, China. xuebinnju@nju.edu.cn.ORCID 0000-0002-0822-6501

Funding

National Natural Science Foundation of China (National Science Foundation of China) T2322010;T2225016;11934008Natural Science Foundation of Jiangsu Province (Jiangsu Provincial Natural Science Foundation) BK20220120
6 · The paper itself

Abstract

While hydrogel-based flexible sensors find extensive applications in fields such as medicine and robotics, their performance can be hindered by the rapid evaporation of water, leading to diminished sensitivity and mechanical durability. Despite the exploration of some effective solutions, such as introducing organic solvents, electrolytes, and elastomer composites, these approaches still suffer from problems including diminished conductivity, interface misalignment, and insufficient protection under dynamic conditions. Inspired by cell membrane structures, we developed an adaptive lipid-integrated bilayer coating (ALIBC) to enhance water retention in hydrogel-based sensors. Lipid layers and long-chain amphiphilic molecules are used as compact coating and anchoring agents on the hydrogel surface, mimicking the roles of lipids and membrane proteins in cell membranes, while spare lipids from aggregates within hydrogels can migrate to the surface to combat dehydration under deformation. This lipid-integrated bilayer coating prevents the water evaporation of hydrogels at both static and dynamic states without affecting the inherent flexibility, conductivity, and no cytotoxicity. Hydrogel-based sensors with ALIBC exhibited significantly enhanced performance in conditions of body temperature, extensive deformation, and long-term dynamic sensing. This work presents a general approach for precisely controlling the water-retaining capacity of hydrogels and hydrogel-based sensors without compromising their intrinsic physical properties.

Indexed as

HydrogelsLipid BilayersWaterBiosensing TechniquesHumansHydrogelsLipid BilayersWater

Identifiers

PMID39632850
PMCPMC11618655

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.