Evidence map›Paper›PMID 39632549›Full record

ReviewESC heart failure2025

Implementation of guideline-recommended medical therapy for patients with heart failure in Europe.

Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes-Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Gut microbiota's role in heart failure.Heart failure reviews · 2025
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maurizio VolterraniCardiopulmonary Department, IRCCS San Raffaele Roma, Rome, Italy.
Petar SeferovicFaculty of Medicine, University of Belgrade, Belgrade, Serbia.
Gianluigi SavareseDepartment of Medicine, Karolinska Institutet, and Heart and Vascular Theme, Karolinska University Hospital, Stockholm, Sweden.
Ilaria SpoletiniCardiopulmonary Department, IRCCS San Raffaele Roma, Rome, Italy.
Egidio ImbalzanoDepartment of Internal Medicine, University of Messina, Messina, Italy.
Antoni Bayes-GenisHeart Institute, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
Ewa JankowskaWroclaw Medical University, Wroclaw, Poland.
Michele SenniCardiology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
Marco MetraDepartment of Medical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.
Ovidiu ChioncelEmergency Institute for Cardiovascular Diseases 'Prof. C.C. Iliescu', Bucharest, Romania.
Andrew J S CoatsUniversity of Warwick, Coventry, UK.
Giuseppe M C RosanoSan Raffaele Open University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0003-4023-2263

Funding

Italian Ministry of Health
6 · The paper itself

Abstract

Physicians' adherence to guideline-recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non-cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life. Thus, the present document aims to address the reasons underlying low implementation and under-dosing of guideline-directed medical therapy in HF and to update a guidance for the initiation and rapid titration of HF drugs. In particular, aim of this document is to provide practical indications for drug implementation, to be applied not only by cardiologists but also by GPs and internal medicine doctors.

Indexed as

Disease ManagementGuideline AdherenceHeart FailurePractice Guidelines as TopicQuality of LifeEuropeHumansguideline‐directed medical therapyheart failurephenotypesworsening heart failure

Identifiers

PMID39632549
PMCPMC11911621

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.