ArticleCancer medicine2024
Meeting Aerobic Physical Activity Guidelines and Associations With Physical Fitness in Men With Metastatic Prostate Cancer: Baseline Results of the Multicentre INTERVAL-GAP4 Trial.
Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02730338 (INTense ExeRcise for SurviVAL Among Men with Metastatic Prostate Cancer), which is not on this map. Cited by 3 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
INTense ExeRcise for SurviVAL Among Men with Metastatic Prostate Cancer (INTERVAL - GAP4): a Multicentre, Randomised, Controlled, Phase III Study
Who cites it
3 citing papers in PubMed.
- Participation and satisfaction of prostate cancer patients on androgen deprivation therapy participating in a virtual supervised group exercise service.BJUI compass · 2026Article
- Prevalence of meeting aerobic physical activity and resistance training guidelines in advanced prostate cancer: a descriptive study of racial and regional disparities in the IRONMAN registry.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Exercise as a new therapeutic modality in oncology: CHALLENGE trial refines survivorship care.Nature reviews. Clinical oncology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThis study compared the physical activity level of men with metastatic prostate cancer at baseline of the multicentre INTERVAL-GAP4 trial to the American Cancer Society guidelines and examined associations with physical fitness.
methodsA total of 140 men on androgen deprivation therapy (ADT) were included in this cross-sectional analysis of baseline data from the INTERVAL-GAP4 trial. Exclusion criteria included a maximum of 1 h of vigorous aerobic exercise or one structured resistance exercise session per week but no restrictions on habitual physical activity. Moderate-to-vigorous physical activity (MVPA) was assessed using a modified Godin-Shephard Leisure-Time Physical Activity Questionnaire. Physical fitness measurements included peak oxygen consumption (VO
resultsTotal self-reported MVPA was 60 (IQR: 0, 180) min per week, with 29% meeting the aerobic physical activity guidelines. There was a statistically significant association of higher MVPA with higher relative VO
conclusionFew men recruited to the INTERVAL-GAP4 trial were meeting aerobic physical activity guidelines at baseline. Higher MVPA was associated with better aerobic capacity and walking performance but not maximal strength in men with metastatic prostate cancer on ADT.
trial registrationClinicalTrials.gov: NCT02730338; German Clinical Trials Register: DRKS00010310.
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