ArticleBrain and behavior2024
Brain Reactivity and Vulnerability to Social Feedback Following Acute Stress in Early Adolescence.
Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neural correlates of acute task-related stress in humans: a systematic review and coordinate-based ALE meta-analysis.Brain imaging and behavior · 2026Pooled it
- Social buffering of the cortisol stress response during the Minnesota Imaging Stress Test in Children.Psychoneuroendocrinology · 2026Trial
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11 authors.
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Abstract
introductionEarly adolescence is a time of high psychosocial stress exposure and high stress reactivity, associated with the development of mental disorders. Understanding how the brain reacts to acute and social stressors during this period might help us detect and protect those at risk.
methodsWe used functional magnetic resonance imaging to investigate acute social stress reactivity in non-clinical adolescents between ages 13 and 15 years (N = 61) with a range of depression scores (Beck Depression Inventory scores 0-32). Participants underwent a modified Montreal Imaging Stress Task (MIST) with psychosocial stress condition consisting of two parts: acute stress (challenging maths) followed by social feedback (positive or negative), separated by brief recovery periods. The test condition was compared to a non-stressful control. We examined brain responses to social feedback relative to the acute stressor and feedback valence.
resultsPsychosocial stress produced differential activation in the paracingulate gyrus, insula, and deactivation in the ventral striatum. Receiving social feedback, compared to acute stress, activated cortical midline regions such as the medial prefrontal cortex and posterior cingulate cortex. Positive feedback increased activity in frontal pole and middle frontal gyrus whereas negative feedback did not show any differential response in the whole group. However, participants with depressive symptoms reacted with higher activation in the posterior cingulate cortex to negative feedback.
conclusionWe show that social feedback after an acute stressor activates regions involved in self-referential processing, with positive feedback eliciting generally higher activation and negative feedback impacting only individuals with vulnerable mood traits during early adolescence.
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