Evidence map›Paper›PMID 39632100›Full record

Trial reportBMJ open respiratory research2024

Differences in uni-dimensional breathlessness measures and thresholds for clinical response in a randomised controlled trial in people with chronic breathlessness: an exploratory study.

Diana Ferreira, Magnus Ekström, Sandra Louw, Philip McCloud, Miriam Johnson, Katherine Clark, David Currow

Abstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diana FerreiraUniversity of Wollongong, Wollongong, New South Wales, Australia.
Magnus EkströmFaculty of Medicine, Department of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund, Sweden.ORCID 0000-0002-7227-5113
Sandra LouwMcCloud Consulting Group, Sydney, New South Wales, Australia.
Philip McCloudMcCloud Consulting Group, Sydney, New South Wales, Australia.
Miriam JohnsonHull York Medical School, The University of Hull, Hull, UK.
Katherine ClarkNorthern Sydney Local Health District, Saint Leonards, New South Wales, Australia.
David CurrowUniversity of Wollongong Faculty of Science Medicine and Health, Wollongong, New South Wales, Australia dcurrow@uow.edu.au.ORCID 0000-0003-1988-1250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOptimally measuring improvements in chronic breathlessness in clinical practice and research continues to evolve. The aim of this study was to consider the performance of uni-dimensional measures in

methodsWe report five measures of breathlessness (intensity:

resultsParticipants (n=284) were mostly elderly men with severe, chronic breathlessness. DISCUSSION: Consistent with other recent work, worst breathlessness may be an important uni-dimensional outcome in evaluating chronic breathlessness clinically and in research. This study does not support a differential between unpleasantness now and breathlessness now, previously observed in laboratory-generated, acute-on-chronic breathlessness. Timeframe for recall (now or the last 24 hours) and the threshold for a clinical meaningful improvement (absolute (8.9 mm) or relative (15%)) affect assessment performance.

Indexed as

DyspneaPulmonary Disease, Chronic ObstructiveAgedAged, 80 and overAnalgesics, OpioidChronic DiseaseDouble-Blind MethodFemaleHumansMaleMiddle AgedMorphineSeverity of Illness IndexTreatment OutcomeAnalgesics, OpioidMorphineCOPD ExacerbationsDrug reactionsPerception of Asthma/Breathlessness

Identifiers

PMID39632100
PMCPMC11624816

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.