ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2025
Evaluation of Renal Perfusion: A Comparative Study between Intravoxel Incoherent Motion (IVIM) Imaging and Arterial Spin Labeling (ASL) to Assess Renal Blood Flow in Rodents.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Assessment of renal interstitial fibrosis in glomerulonephritis using compartmental and non-compartmental diffusion magnetic resonance imaging.La Radiologia medica · 2026Article
- WCCAN: Windowed Cross-contrast Attention Network for Multi-contrast Brain MR Image Super-resolution.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
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Abstract
purposeTo compare diagnostic reliability between an intravoxel incoherent motion (IVIM) imaging and an arterial spin labeling (ASL) in assessment of renal blood flow in rodents.
methodsWe first evaluated 3 different fitting methods on 5 datasets of diffusion-weighted imaging (DWI) with 10 b-values (0-1000 s/mm
resultsThe CVs in all IVIM parameters were the lowest in the fitting method that estimated pseudo-diffusion parameters after a fixed true-diffusion was determined where the pseudo- and true-diffusion coefficients had no correlation. The RBF substantially reduced (~50%, P < 0.001) due to the AKI onset; however, no pseudo-diffusion parameters in any of 3 fitting methods could not detect the change. Further, any pseudo-diffusion parameters showed no correlation with the RBF.
conclusionPseudo-diffusion parameters in the IVIM concept were not reliable to estimate RBF in the study. Since the kidney has a unique profile in the "tissue flow", our data indicate that study design and interpretation of results needs to be carefully considered when IVIM imaging is used for evaluation of blood flow in tissue, especially in the kidney.
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