Evidence map›Paper›PMID 39630893›Full record

ArticleScience advances2024

A trafficking regulatory subnetwork governs α

Horacio Maldonado, Marcel Dreger, Lara D Bedgood, Theano Kyriakou, Katarzyna I Wolanska, Megan E Rigby, Valeria E Marotta, Justine M Webster, Jun Wang, Emma V Rusilowicz-Jones and 5 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. GDI2 protein: research progress and its mechanisms in diseases.Frontiers in cell and developmental biology · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Horacio MaldonadoInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0000-0002-7017-5215
Marcel DregerDivision of Immunology, Immunity to Infection and Respiratory Medicine, Faculty of Biology, Medicine & Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0002-2852-0345
Lara D BedgoodInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
Theano KyriakouInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0009-0002-0978-668X
Katarzyna I WolanskaInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0000-0002-2990-0710
Megan E RigbyInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0009-0002-4738-4892
Valeria E MarottaInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0009-0008-5085-0325
Justine M WebsterInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.
Jun WangCentre for Tumour Biology, Barts Cancer Institute, Queen Mary University London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.ORCID 0000-0003-2509-9599
Emma V Rusilowicz-JonesInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0000-0001-7496-3318
John F MarshallCentre for Tumour Biology, Barts Cancer Institute, Queen Mary University London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK.
Judy M CoulsonInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0000-0003-2191-2001
Iain R MacphersonWolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow G61 1QH, UK.ORCID 0000-0003-4295-8885
Adam HurlstoneDivision of Immunology, Immunity to Infection and Respiratory Medicine, Faculty of Biology, Medicine & Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0001-5260-9457
Mark R MorganInstitute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 3BX, UK.ORCID 0000-0001-7728-9883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HER2 and α

Indexed as

Breast NeoplasmsDrug Resistance, NeoplasmErb-b2 Receptor Tyrosine KinasesIntegrinsrab5 GTP-Binding Proteinsrab7 GTP-Binding Proteinsrab GTP-Binding ProteinsTrastuzumabAnimalsAntigens, NeoplasmCell Line, TumorCell MovementFemaleHumansMiceNeoplasm InvasivenessAntigens, NeoplasmERBB2 protein, humanErb-b2 Receptor Tyrosine Kinasesintegrin alphavbeta6IntegrinsRAB5C protein, humanrab5 GTP-Binding Proteinsrab7 GTP-Binding Proteinsrab7 GTP-binding proteins, humanrab GTP-Binding ProteinsTrastuzumab

Identifiers

PMID39630893
PMCPMC11616693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.