Evidence map›Paper›PMID 39630824›Full record

ReviewPloS one2024

Coronary embolism in left-sided infective endocarditis. A retrospective analysis from a high-volume surgical centre and review of the literature.

Ruggero Mazzotta, Matteo Orlandi, Valentina Scheggi, Niccolò Marchionni, Pierluigi Stefàno

Abstract readReview
In one paragraph

Review in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruggero MazzottaDivision of General Cardiology, Cardiothoracovascular Department, Careggi University Hospital, Florence, Italy.
Matteo OrlandiDivision of General Cardiology, Cardiothoracovascular Department, Careggi University Hospital, Florence, Italy.ORCID 0009-0002-6617-1040
Valentina ScheggiDivision of Cardiovascular and Perioperative Medicine, Cardiothoracovascular Department, Careggi University Hospital, Florence, Italy.
Niccolò MarchionniDivision of General Cardiology, Cardiothoracovascular Department, Careggi University Hospital, Florence, Italy.
Pierluigi StefànoDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID 0000-0001-8338-3016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeptic embolization is a common and potentially life-threatening complication of infective endocarditis (IE), with a prevalence of 22-50%. While acute coronary syndrome secondary to septic embolism is rare, it poses significant risks.

aimsThis study examines coronary embolism (CE) in left-sided IE, describing clinical characteristics and outcomes.

methodsWe retrospectively analysed 649 patients with non-device-related left-sided IE treated between January 2013 and December 2023 in a high-volume surgical centre. CE was diagnosed via ECG, clinical and laboratory signs of acute coronary syndrome, and confirmed by coronary angiography or magnetic resonance imaging. All patients were treated according to current European Society of Cardiology guidelines. A structured follow-up was performed.

resultsAmong patients included in the study, surgery was performed in 514 (79%) patients. Median follow-up duration was 4.7 years. CE occurred in 8 (1.2%) patients, and 6 (80%) of them were treated surgically. We found no significant differences in overall mortality rate between patients with or without CE (p = 0.65). Finally, cerebral embolism was significantly more frequent in patients with than without CE (75% vs 25%, p = 0.006, post-hoc power 87.8%).

conclusionCE is a rare but severe complication of IE, significantly associated with cerebral embolism. Early recognition and treatment are crucial to improve patient outcomes. Multicentre studies with larger patient populations are needed to further elucidate risk factors and enhance prognosis for CE in IE patients.

Indexed as

EmbolismEndocarditisAdultAgedCoronary AngiographyFemaleHumansIntracranial EmbolismMaleMiddle AgedRetrospective Studies

Identifiers

PMID39630824
PMCPMC11616836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.