ArticleRevista da Associacao Medica Brasileira (1992)2024
Predictive efficacy of immature granulocytes in acute complicated appendicitis.
Article in Revista da Associacao Medica Brasileira (1992), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The Role of Immature Granulocyte Count and Percentage as Novel Indicators of Systemic Inflammation in Plaque Psoriasis.Journal of clinical medicine · 2026Article
- Predictors of prolonged hospitalization and inflammation severity in acute appendicitis: a retrospective cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Immature granulocyte: an early predictor of strangulated adhesive small bowel obstruction.BMC gastroenterology · 2025Article
- Hyperbilirubinemia as a Marker for Complicated Acute Appendicitis: A Systematic Review.Cureus · 2025Review
- Role of immature granulocytes in monitoring sepsis treatment.BMC anesthesiology · 2025Observational
- Immature granulocyte and neutrophil-to-lymphocyte ratio in acute appendicitis: new markers to strengthen diagnosis.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Comment on "Predictive efficacy of immature granulocytes in acute complicated appendicitis".Revista da Associacao Medica Brasileira (1992) · 2025Article
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6 authors.
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Abstract
objectiveAcute appendicitis is the most common cause of acute abdomen. It is important to differentiate between complicated and uncomplicated appendicitis before surgery in the emergency department. Recently, immature granulocytes have become one of the biomarkers used as predictors of inflammation. The aim of this study was to determine whether immature granulocyte levels are a biomarker that can predict whether acute appendicitis is complicated or not in patients admitted to the emergency department.
methodsPatients aged 18 years and older who presented to the emergency department between May 1, 2023, and April 30, 2024, and were diagnosed with appendicitis were included in the study. Patients with a histopathologic diagnosis of acute appendicitis were divided into two groups: acute simple appendicitis (n=149) and acute complicated appendicitis (n=103). Demographic characteristics, imaging results, and laboratory results were recorded.
resultsWhite blood cell, neutrophil count and percentage, lymphocyte count and percentage, immature granulocyte count and percentage, direct bilirubin, C-reactive protein, and procalcitonin values were found to be significantly higher in the complicated appendicitis group than in the uncomplicated group (p-values; 0.001, <0.001, <0.001, <0.001, 0.001, <0.001, <0.001, <0.001, <0.001, 0.016, <0.001, and 0.001, respectively). The immature granulocyte percentage was 92% specific for the diagnosis of complicated appendicitis at a cut-off value of 0.6.
conclusionThe immature granulocyte percentage may be useful as a predictive biomarker in the diagnosis of complicated acute appendicitis with a specificity of 92%. Additionally, the immature granulocyte percentage has a higher discrimination power than the immature granulocyte count, C-reactive protein, and procalcitonin.
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