ArticleRevista da Associacao Medica Brasileira (1992)2024
Liver/spleen magnetic resonance elastography and T1/T2 mapping in chronic liver disease: a prospective study.
Article in Revista da Associacao Medica Brasileira (1992), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
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3 citing papers in PubMed.
- Reliable diagnosis of liver focal nodular hyperplasia by a combination of T2 weighted signal and three diffusion magnetic resonance metrics of diffusion-derived 'vessel density', slow diffusion coefficient, and apparent diffusion coefficient: a validation study of two centers' data.Quantitative imaging in medicine and surgery · 2026Article
- Liver Tissue Mapping in Transfusion-Dependent β-Thalassemia: Reproducibility and Clinical Insights from Multiparametric MRI.Diagnostics (Basel, Switzerland) · 2025Article
- An explanation for why tissues with T2 of around 70 milliseconds always measure low MRI apparent diffusion coefficient (ADC).Quantitative imaging in medicine and surgery · 2025Article
Corrections and comments
- Erratum issuedErratum.2025
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aims to compare liver and spleen stiffness measurements using magnetic resonance elastography with T1 and T2 relaxation times in patients with chronic liver disease.
methodsA total of 75 chronic liver disease patients and 25 healthy volunteers underwent MR. Patients with significant liver fat and iron accumulation were excluded. Student's t-test was employed to compare magnetic resonance elastography and T1/T2 values. Pearson's correlation test was used to assess the relationship between magnetic resonance elastography and T1/T2 values.
resultsLiver magnetic resonance elastography showed a significant moderate positive correlation with liver T1 mapping (r=0.51, p<0.001) and liver T2 mapping (r=0.30, p=0.009) in patients. Spleen magnetic resonance elastography exhibited a significant moderate positive correlation with spleen T2 mapping (r=0.37, p=0.001). However, there was no significant correlation between spleen magnetic resonance elastography and spleen T1 mapping in patients. Spleen magnetic resonance elastography was moderately positively correlated with liver magnetic resonance elastography (r=0.30, p=0.01), and spleen volume showed positive correlations with spleen magnetic resonance elastography, spleen T1 mapping, and spleen T2 mapping. Cut-off values for liver magnetic resonance elastography, liver T1 mapping, and liver T2 mapping in patient and control groups were 2.6 kPa (AUC=0.97), 619 ms (AUC=0.90), and 52.5 ms (AUC=0.62), respectively.
conclusionRelaxation methods offer noninvasive imaging without additional equipment. Liver T1 mapping may serve as an alternative to magnetic resonance elastography for chronic liver patient follow-up, while spleen T1 mapping is not reliable.
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