Evidence map›Paper›PMID 39630462›Full record

ArticleInvestigative ophthalmology & visual science2024

Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia.

Ibrahim M Quagraine, Jordan Murray, Gokce Busra Cakir, Sinem Balta Beylergil, Alexa Kaudy, Aasef G Shaikh, Fatema F Ghasia

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ibrahim M QuagraineDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States.
Jordan MurrayCole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States.
Gokce Busra CakirCole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States.
Sinem Balta BeylergilCole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States.
Alexa KaudyCole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States.
Aasef G ShaikhDaroff-Dell'Osso Ocular Motility Laboratory, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio, United States.
Fatema F GhasiaCole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States.

Funding

Cole Eye Institute Vision Science Training ProgramT32EY024236 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI ANAND-APTE, BELA · 2015 to 2025
$1.0M
Deep brain stimulation for visuomotor function in Parkinson's diseaseI21RX003878 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI SHAIKH, AASEF G · 2022 to 2023
–
NEI NIH HHS T32 EY024236RRD VA I21 RX003878
6 · The paper itself

Abstract

Purpose: This study uses eye tracking to investigate how varying fellow eye (FE) contrast during dichoptic video viewing influences eye movement patterns, and their associations with interocular suppression, visual acuity, and stereoacuity deficit in amblyopia. Methods: Eye movements of 27 amblyopic and 8 healthy control participants were recorded during dichoptic viewing of stationary dots and videos with FE contrasts (100%, 50%, 25%, and 10%). Analysis included durations the amblyopic and FE spent in different stimulus regions, fixation switches, and eye deviation, and correlating these with suppression, visual acuity, and stereoacuity. Results: Participants with pronounced suppression, visual acuity, and stereoacuity deficits demonstrated reduced amblyopic eye fixation in the amblyopic eye (AE) region at 100% FE contrast. Lowering FE contrast increased amblyopic eye duration in stimuli presented within the AE region, notably in anisometropic and treated strabismic participants, and strabismic participants exhibiting fixation switches during viewing of dichoptic stationary dots. Even at lower FE contrasts, participants with greater stereoacuity and visual acuity deficits continued to exhibit diminished AE fixation in the AE region. Increased eye deviation was seen in strabismic participants with lowering of FE contrasts. Conclusions: Dichoptic contrast modulation holds promise for reducing suppression with responses varying by amblyopia type and visual function deficits. Larger strabismic angles may hinder binocular benefits of dichoptic treatments. Fixation switches may serve as an indicator of favorable outcomes. Eye tracking is crucial for understanding these dynamics, providing essential insights into visual attention dynamics of the FE and AE, and may serve as a valuable tool in optimization of amblyopia treatments.

Indexed as

AmblyopiaEye MovementsVision, BinocularVisual AcuityAdolescentAdultContrast SensitivityDepth PerceptionEye-Tracking TechnologyFemaleFixation, OcularHumansMaleMiddle AgedVideo RecordingYoung Adult

Identifiers

PMID39630462
PMCPMC11627246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.